SCHEMBL13385296

SCHEMBL13385296

C=Cc1ccc(N(c2ccc(OC)cc2)c2cccc(OC)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RELA Q04206 4/20 0.49
MTNR1A P48039 2/20 0.44
MTNR1B P49286 2/20 0.44
ALOX15 P16050 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
ENPP2 Q13822 1/20 0.40
CHRM5 P08912 1/20 0.39
NFE2L2 Q16236 2/20 0.39
APP P05067 1/20 0.39
CYP19A1 P11511 1/20 0.39
NQO2 P16083 1/20 0.39
CHRNA7 P36544 1/20 0.39
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487163 0.97 RELA (0.44) RELAMTNR1AMTNR1BALOX15ENPP2
SCHEMBL5491844 0.91 ADRA2A (0.43) RELAMTNR1AMTNR1BALOX15CHRM5
SCHEMBL17973786 0.87 TRPA1 (0.52) RELAMTNR1AMTNR1BTRPA1
SCHEMBL12236928 0.87 TRPA1 (0.52) RELAMTNR1AMTNR1BTRPA1
SCHEMBL11987113 0.87 ALDH1A1 (0.47) RELAALOX15NFE2L2CYP19A1NQO2
SCHEMBL5289507 0.87 ALDH1A1 (0.47) RELAALOX15NFE2L2CYP19A1NQO2
SCHEMBL8944101 0.87 HSD17B2 (0.50) RELAMTNR1AMTNR1BALOX15HSD17B1
SCHEMBL13404835 0.86 MTNR1B (0.42) RELAMTNR1AMTNR1BALOX15
SCHEMBL13385299 0.85 ALDH1A1 (0.58) RELAMTNR1AMTNR1BALOX15HSD17B1
SCHEMBL5843982 0.85 RELA (0.48) RELANFE2L2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700248-B2 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK COMPANY (US) 2010-04-20 US disclosed
US-7700248-B2 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK COMPANY (US) 2010-04-20 US disclosed