Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135891 | 0.98 | LMNA (0.39) | APEX1NPSR1DNM1LMNAMEN1 | |
| Bromide SCHEMBL30494329 | 0.95 | MEN1 (0.42) | APEX1NPSR1DNM1LMNAMEN1 | |
| Water SCHEMBL3346699 | 0.95 | APAF1 (0.39) | APEX1NPSR1DNM1LMNAMEN1 | |
| SCHEMBL13197515 | 0.84 | LMNA (0.53) | DNM1LMNAKMT2AHSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28509982 | 0.83 | LMNA (0.42) | LMNA | |
| Hydrochloric Acid SCHEMBL31233472 | 0.83 | LMNA (0.44) | DNM1LMNAKMT2AHSP90AA1RAD52 | |
| SCHEMBL17937796 | 0.80 | LMNA (0.41) | APEX1NPSR1DNM1LMNAMEN1 | |
| SCHEMBL15305644 | 0.80 | LMNA (0.37) | LMNABBOX1 | |
| Hydrochloric Acid SCHEMBL1994696 | 0.80 | DNM1 (0.39) | DNM1LMNAKDM4EPMP22 | |
| Hydrochloric Acid SCHEMBL6813018 | 0.78 | SLC22A1 (0.50) | DNM1LMNASMN1; SMN2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930246-A | Shield residue soil synchronous grouting material and preparation method thereof | 北京科技大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119867087-A | Biological agent containing arbuscular mycorrhizal fungi and preparation method thereof | 山东德浩化学有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-118480386-A | High-efficiency coking inhibitor and preparation method thereof | 河北德福佳昌化工有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-115155328-B | Polymer ultrafiltration membrane for sewage treatment and preparation method thereof | 安庆市鑫祥瑞环保科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117258127-A | Insulin release controllable microneedle patch with blood glucose concentration response and preparation method thereof | 浙江大学 | 2023-12-22 | — | — | CN | claimed |
| CN-114855473-B | Dyeing method of cellulose fiber material | 青岛大学 | 2023-12-15 | — | — | CN | claimed |
| CN-114341072-B | Textured glass articles and methods of making the same | 康宁股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116391725-A | Hydrophobic bactericide and preparation method thereof | 陈雄胜 | 2023-07-07 | — | — | CN | claimed |
| CN-113332172-B | Preparation method of nanofiber gel membrane based on bagasse pith quaternary ammonium salt polysaccharide | 昆明理工大学 | 2023-04-25 | — | — | CN | claimed |
| CN-115814956-A | Beneficiation method for low-grade spodumene ores | 江西理工大学 | 2023-03-21 | — | — | CN | claimed |
| US-20160079590-A1 | CATHODE, LITHIUM AIR BATTERY INCLUDING THE SAME, AND METHOD OF PREPARING THE CATHODE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-03-17 | — | — | US | claimed |
| US-20110143147-A1 | Agent for providing substrates based on cellulose and/or starch with water repellent and simultaneously antifungal, antibacterial insect-repellent and antialgal properties | DEGUSSA GMBH (DE) | 2011-06-16 | — | — | US | claimed |
| US-7914960-B2 | Additive containing charge transport layer photoconductors | XEROX CORPORATION (US) | 2011-03-29 | — | — | US | claimed |
| US-20090092913-A1 | ADDITIVE CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-20090092911-A1 | ADDITIVE CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| EP-1773918-A1 | AGENT FOR PROVIDING SUBSTRATES BASED ON CELLULOSE AND/OR STARCH WITH WATER-REPELLENT AND SIMULTANEOUSLY ANTIFUNGAL, ANTIBACTERIAL, INSECT-REPELLENT AND ANTIALGAL PROPERTIES | Degussa GmbH (DE) | 2007-04-18 | — | — | EP | claimed |
| WO-2006010667-A1 | AGENT FOR PROVIDING SUBSTRATES BASED ON CELLULOSE AND/OR STARCH WITH WATER-REPELLENT AND SIMULTANEOUSLY ANTIFUNGAL, ANTIBACTERIAL, INSECT-REPELLENT AND ANTIALGAL PROPERTIES | DEGUSSA AG (DE) | 2006-02-02 | — | — | WO | claimed |
| US-5919552-A | Coated substrates and methods | XEROX CORPORATION (US) | 1999-07-06 | — | — | US | claimed |
| WO-1997045498-A1 | HIGHLY TINTABLE, ABRASION-RESISTANT COATING COMPOSITIONS | SDC COATINGS, INC. (US) | 1997-12-04 | — | — | WO | claimed |
| US-5616533-A | Chemically active ceramic compositions with a thiol and/or amine moiety | SYRACUSE UNIVERSITY (US) | 1997-04-01 | — | — | US | claimed |