Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112936 | 0.83 | TDP1 (0.49) | NOTUMMGLLCYP1A2AVPR1AALDH1A1 | |
| SCHEMBL19604863 | 0.80 | FAAH (0.39) | KEAP1FAAHMGLLCYP1A2CYP2D6 | |
| SCHEMBL1562739 | 0.78 | AVPR1A (0.56) | AVPR1AALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL17153859 | 0.77 | NOTUM (0.39) | NOTUMKEAP1FAAHMGLLCYP1A2 | |
| SCHEMBL932177 | 0.74 | ESR1 (0.48) | NOTUMALDH1A1LMNANPC1MAPT | |
| SCHEMBL11996354 | 0.74 | ALDH1A1 (0.51) | NOTUMCYP2C19ALDH1A1LMNANPC1 | |
| SCHEMBL14132456 | 0.73 | RXFP1 (0.55) | NOTUMCYP1A2CYP2C19AVPR1AALDH1A1 | |
| SCHEMBL14583724 | 0.73 | TDP1 (0.49) | NOTUMMGLLACHECYP1A2CYP2D6 | |
| SCHEMBL8740860 | 0.73 | LMNA (0.39) | CYP2D6CYP2C19AVPR1ALMNA | |
| SCHEMBL16720842 | 0.72 | ALDH1A1 (0.59) | NOTUMKEAP1FAAHMGLLACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002327-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | TSINGHUA UNIVERSITY (CN) | 2023-01-05 | — | — | US | disclosed |
| CN-112174903-B | Small molecule modulators of TLR8 | 清华大学 | 2022-07-12 | — | — | CN | disclosed |
| EP-3998255-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | Tsinghua University (CN) | 2022-05-18 | — | — | EP | disclosed |
| WO-2021000755-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | 清华大学 | 2021-01-07 | — | — | WO | disclosed |
| CN-112174903-A | Small molecule modulators of TLR8 | 清华大学 | 2021-01-05 | — | — | CN | disclosed |
| EP-1975708-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2015-04-22 | — | — | EP | disclosed |
| US-7695888-B2 | Photosensitive lithographic printing plate | FUJIFILM CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7695888-B2 | Photosensitive lithographic printing plate | FUJIFILM CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| EP-1975708-A2 | Lithographic printing plate precursor | FUJIFILM Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002327-A1 | SMALL-MOLECULE REGULATOR OF TLR8 | TLR8, TLR6, TLR1 | NOTUM 4024/4885KEAP1 2095/4885FAAH 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.