Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204343 | 0.80 | POLB (0.46) | L3MBTL1POLBNPC1MAPTRAB9A | |
| SCHEMBL28464543 | 0.77 | BACE1 (0.47) | L3MBTL1BACE1MAPK1HSD17B10NR1H2 | |
| SCHEMBL25422381 | 0.76 | USP7 (0.51) | L3MBTL1POLBADORA2AADORA3ADORA1 | |
| SCHEMBL19462191 | 0.75 | PRKACA (0.44) | L3MBTL1ADORA2AASIC3AURKAHSP90AA1 | |
| SCHEMBL15865506 | 0.73 | NOS2 (0.54) | ADORA2AASIC3AURKAHSP90AA1PRKACA | |
| SCHEMBL3781200 | 0.73 | FABP4 (0.47) | L3MBTL1POLBADORA2AADORA3ADORA1 | |
| SCHEMBL29360194 | 0.73 | GSK3B (0.46) | L3MBTL1ADORA2AASIC3AURKAHSP90AA1 | |
| SCHEMBL4647645 | 0.73 | GSK3B (0.46) | L3MBTL1ADORA2AASIC3AURKAHSP90AA1 | |
| SCHEMBL29435659 | 0.72 | NOS3 (0.46) | POLBBACE1MAPK1HSD17B10HTT | |
| SCHEMBL157195 | 0.72 | NOS3 (0.46) | POLBBACE1MAPK1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228366-B1 | Method for producing 2-amino-4-(halogenalkyl)pyridine derivatives by means of cyclization of suitable nitrile precursors with nitrogen combinations | ARCHIMICA GMBH (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-8063226-B2 | Process for preparing 2-amino-4-(haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | ARCHIMICA GMBH (DE) | 2011-11-22 | — | — | US | disclosed |
| US-8063226-B2 | Process for preparing 2-amino-4-(haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | ARCHIMICA GMBH (DE) | 2011-11-22 | — | — | US | disclosed |
| US-8063226-B2 | Process for preparing 2-amino-4-(haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | ARCHIMICA GMBH (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20100234607-A1 | Process for preparing 2-amino-4- (haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | EUTICALS GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234607-A1 | Process for preparing 2-amino-4- (haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | EUTICALS GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234607-A1 | Process for preparing 2-amino-4- (haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | EUTICALS GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-2228366-A1 | Method for producing 2-amino-4-(halogenalkyl)pyridine derivatives by means of cyclization of suitable nitrile precursors with nitrogen combinations | Archimica GmbH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-2228366-A1 | Method for producing 2-amino-4-(halogenalkyl)pyridine derivatives by means of cyclization of suitable nitrile precursors with nitrogen combinations | Archimica GmbH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-0619804-A1 | HERBICIDAL ACYLATED AMINO-(PHENYL- OR PYRIDINYL- OR THIENYL-)-PHENYL DERIVATIVES. | DU PONT (US) | 1994-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234607-A1 | Process for preparing 2-amino-4- (haloalkyl) pyridine derivatives by cyclizing suitable nitrile precursors with nitrogen compounds | NISCH, NIT2, ASNS | L3MBTL1 4875/4885POLB 427/4885ADORA2A 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.