Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.55 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phyllocladene SCHEMBL1006869 | 0.81 | HSD11B1 (0.72) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Phyllocladene SCHEMBL156928 | 0.81 | HSD11B1 (0.72) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| SCHEMBL13401510 | 0.77 | PTPN1 (0.58) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| SCHEMBL3492706 | 0.77 | PTPN1 (0.58) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| SCHEMBL3492708 | 0.77 | PTPN1 (0.58) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Phyllocladene SCHEMBL20538769 | 0.73 | PTPN1 (0.65) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Phyllocladene SCHEMBL16414456 | 0.73 | PTPN1 (0.65) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Kaurenoic Acid SCHEMBL266944 | 0.72 | PTPN1 (1.00) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Kaurenoic Acid SCHEMBL1921625 | 0.72 | PTPN1 (1.00) | PTPN1HSD11B1HSD11B2BCHEACHE | |
| Kaurenoic Acid SCHEMBL21803663 | 0.72 | PTPN1 (1.00) | PTPN1HSD11B1HSD11B2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | SORD, CASP3, TXNRD2 | PTPN1 3492/4885HSD11B1 187/4885HSD11B2 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.