SCHEMBL13402335

SCHEMBL13402335

CCCOCCOC(=O)NC1C(O)CC(OC(C)C)(C(=O)O)OC1C(O)C(O)CO

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 2/20 0.43
▸ SIGLEC7 Q9Y286 5/20 0.38
▸ SELL P14151 1/20 0.38
▸ SELP P16109 1/20 0.38
▸ CD22 P20273 5/20 0.38
▸ MAG P20916 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341462 0.93 NANP (0.47) NANPSIGLEC7SELLSELPCD22
SCHEMBL12341443 0.85 NANP (0.44) NANPCD22MAG
SCHEMBL12730475 0.85 NANP (0.44) NANPCD22MAG
SCHEMBL14454528 0.85 NANP (0.44) NANPCD22MAG
SCHEMBL13402333 0.83 CD22 (0.38) NANPCD22
SCHEMBL29226087 0.83 NANP (0.60) NANPSIGLEC7SELLSELPCD22
SCHEMBL13402336 0.82 CD22 (0.37) NANPSIGLEC7SELPCD22
SCHEMBL13402334 0.81 CD22 (0.38) NANPCD22MAG
SCHEMBL14000588 0.81 NANP (0.45) NANPSIGLEC7SELLSELPCD22
SCHEMBL13839153 0.81 NANP (0.49) NANPSIGLEC7SELLSELPCD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187546-B2 Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants NOVO NORDISK A/S (DK) 2015-11-17 — — US disclosed
US-20100081791-A1 GLYCOPEGYLATED FACTOR IX NOVO NORDISK A/S (DK) 2010-04-01 — — US disclosed
US-20100041872-A1 GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES NOVO NORDISK A/S (DK) 2010-02-18 — — US disclosed
US-20090305967-A1 GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA NOVO NORDISK A/S (DK) 2009-12-10 — — US disclosed
US-20090124544-A1 COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS NEOSE TECHNOLOGIES ,INC. A DELAWARE CORPORATION 2009-05-14 — — US disclosed
US-20090028822-A1 Glycopegylated Interferon Alpha NEOSE TECHNOLOGIES, INC. (US) 2009-01-29 — — US disclosed
US-20080300173-A1 Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] NOVO NORDISK A/S (DK) 2008-12-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090028822-A1 Glycopegylated Interferon Alpha IFNG, IFNAR1, OGT NANP 366/4885SIGLEC7 52/4885SELL 243/4885
US-20090305967-A1 GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA F7, F13B, F13A1 NANP 431/4885SIGLEC7 23/4885SELL 190/4885
US-20100081791-A1 GLYCOPEGYLATED FACTOR IX F9, F13A1, F13B NANP 156/4885SIGLEC7 46/4885SELL 86/4885
US-20080300173-A1 Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] GLP1R, GIPR, IAPP NANP 896/4885SIGLEC7 100/4885SELL 280/4885
US-20100041872-A1 GLYCEROL LINKED PEGYLATED SUGARS AND GLYCOPEPTIDES UGCG, B3GAT3, UGGT1 NANP 306/4885SIGLEC7 16/4885SELL 805/4885
US-20090124544-A1 COMPOSITIONS AND METHODS FOR THE PREPARATION OF PROTEASE RESISTANT HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS GHITM, PTMS, GHRHR NANP 386/4885SIGLEC7 853/4885SELL 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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