Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21774961 | 0.98 | FDPS (0.42) | FDPSADORA2BALDH1A1CYP2C9TSHR | |
| SCHEMBL8443845 | 0.88 | FDPS (0.41) | FDPSADORA2BALDH1A1CYP2C9TSHR | |
| SCHEMBL20011271 | 0.80 | FDPS (0.44) | FDPSADORA2BALDH1A1ADORA2ALMNA | |
| SCHEMBL7037181 | 0.77 | LMNA (0.51) | FDPSALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL13384363 | 0.76 | ADORA2B (0.38) | ADORA2BALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL24596147 | 0.75 | FDPS (0.41) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL24596179 | 0.75 | FDPS (0.41) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11745655 | 0.75 | — | — | |
| SCHEMBL23657200 | 0.72 | MEN1 (0.42) | FDPSADORA2BALDH1A1HPGDHSD17B10 | |
| SCHEMBL14414715 | 0.70 | ADORA2A (0.53) | ADORA2BALDH1A1TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273146-A1 | TRICYCLIC COMPOUND AND USE THEREOF | Nanjing Zaiming Pharmaceutical Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |