Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.64 |
| ▸ | RARG | P13631 | 11/20 | 0.64 |
| ▸ | RARA | P10276 | 9/20 | 0.64 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 10/20 | 0.59 |
| ▸ | RXRB | P28702 | 8/20 | 0.59 |
| ▸ | RXRG | P48443 | 6/20 | 0.59 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246895 | 0.86 | RARB (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL2225520 | 0.85 | RARB (0.62) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8733241 | 0.82 | RARB (0.83) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL19072651 | 0.81 | CYP3A4 (0.63) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL846110 | 0.80 | RARB (0.81) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL2195224 | 0.80 | RXRA (0.66) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL29827631 | 0.80 | RARB (0.81) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7621355 | 0.80 | RARA (0.82) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL2788640 | 0.79 | CYP3A4 (0.70) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL1022234 | 0.79 | RXRA (0.63) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772327-B2 | Phenylpropionic acid derivative and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8334314-B2 | Phenylpropionic acid derivative and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100093819-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | RARB 2328/4885RARG 2637/4885RARA 2137/4885 |
| US-20100093819-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | RARB 2328/4885RARG 2637/4885RARA 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.