Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300121 | 0.84 | HTR2B (0.35) | — | |
| SCHEMBL6321996 | 0.84 | HTR2B (0.35) | — | |
| SCHEMBL6314507 | 0.80 | KDM4E (0.41) | — | |
| SCHEMBL1534233 | 0.79 | HTR2B (0.44) | — | |
| SCHEMBL13390599 | 0.78 | TP53 (0.36) | — | |
| SCHEMBL11963453 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL13408606 | 0.75 | ACMSD (0.34) | RARARARBRARG | |
| SCHEMBL11963399 | 0.74 | KMT2A (0.37) | — | |
| SCHEMBL1314947 | 0.74 | KMT2A (0.37) | — | |
| SCHEMBL11963290 | 0.74 | KMT2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730917-B2 | Desferrithiocin polyether analogues | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160022645-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-9174948-B2 | Desferrithiocin polyether analogues | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130210870-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8324397-B2 | Desferrithiocin polyether analogues | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100093812-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022645-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | HAMP, SLC40A1, FTH1 | PDCD1 3052/4885CD274 3644/4885RARA 2953/4885 |
| US-20100093812-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | SLC40A1, HAMP, FTH1 | PDCD1 2942/4885CD274 3556/4885RARA 3133/4885 |
| US-20130210870-A1 | DESFERRITHIOCIN POLYETHER ANALOGUES | HAMP, SLC40A1, FTH1 | PDCD1 3052/4885CD274 3644/4885RARA 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.