Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273109 | 0.88 | TRPA1 (0.35) | TRPA1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL13409342 | 0.82 | PDE1B (0.39) | LRRK2TRPM8TRPA1LMNAMAPT | |
| SCHEMBL13409340 | 0.81 | CYP19A1 (0.43) | LRRK2TRPM8TRPA1MAPTCYP2C19 | |
| SCHEMBL8274257 | 0.77 | LMNA (0.36) | LMNAMAPTCYP2C19 | |
| SCHEMBL13409320 | 0.77 | PLAU (0.49) | LRRK2TRPM8LMNAMAPTATM | |
| SCHEMBL1536394 | 0.77 | LMNA (0.40) | LMNAMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13409347 | 0.73 | HPGD (0.35) | LRRK2 | |
| SCHEMBL13409351 | 0.72 | LRRK2 (0.36) | LRRK2TRPM8MAPTATMCYP2C19 | |
| SCHEMBL13409304 | 0.67 | TRPM8 (0.51) | TRPM8LMNAMAPTATMCYP1A2 | |
| SCHEMBL13409373 | 0.67 | CYP1A2 (0.45) | LRRK2TRPM8MAPTATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |