Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 5/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691153 | 0.78 | LMNA (0.44) | CYP2A6 | |
| SCHEMBL18523245 | 0.78 | PLG (0.35) | CYP2A6PLAUPLGPLAT | |
| SCHEMBL3735578 | 0.77 | CYP2A6 (0.44) | CYP2A6 | |
| SCHEMBL12405291 | 0.73 | HPRT1 (0.36) | ACHE | |
| SCHEMBL30497136 | 0.73 | PLAU (0.56) | CYP2A6PLAUPLGPLAT | |
| SCHEMBL12053800 | 0.73 | TRPA1 (0.41) | CYP2A6 | |
| SCHEMBL2617536 | 0.73 | NR4A2 (0.43) | CYP2A6 | |
| SCHEMBL29024926 | 0.73 | CTDSP1 (0.50) | PLAUPLGPLATACHE | |
| SCHEMBL582930 | 0.73 | PLAU (0.56) | CYP2A6PLAUPLGPLAT | |
| SCHEMBL29339572 | 0.73 | PLG (0.47) | PLAUPLGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | SHIONOGI & CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099676-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | MMP13, MMP3, MMP26 | CYP2A6 753/4885PLAU 69/4885PLG 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.