Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743135 | 0.90 | ADORA3 (0.46) | ADORA3KDM4EHPGDSLC6A2SLC6A4 | |
| SCHEMBL16775316 | 0.88 | ADORA3 (0.48) | ADORA3SLC6A2MAPTHTTSMN1; SMN2 | |
| SCHEMBL16405351 | 0.86 | ADORA3 (0.49) | ADORA3SLC6A2MAPTHTTSMN1; SMN2 | |
| SCHEMBL15336467 | 0.84 | ADORA3 (0.50) | ADORA3KDM4EHPGDSLC6A4SLC6A3 | |
| SCHEMBL14877709 | 0.83 | KDM4E (0.47) | ADORA3KDM4EHPGDSLC6A4SLC6A3 | |
| SCHEMBL12021704 | 0.83 | MAPT (0.47) | ADORA3KDM4EHPGDSLC6A2SLC6A4 | |
| SCHEMBL410353 | 0.83 | LMNA (0.48) | MAPTNPC1RAB9ALMNAMMP13 | |
| SCHEMBL13346992 | 0.83 | PPARA (0.45) | ADORA3MAPTHTTSMN1; SMN2NPC1 | |
| SCHEMBL17298988 | 0.82 | ADORA3 (0.52) | ADORA3MAPTHTTSMN1; SMN2NPC1 | |
| SCHEMBL16158988 | 0.81 | ADORA3 (0.43) | ADORA3KDM4EHPGDSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700696-B2 | Polycarbonate composition having improved scratch resistance, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-04-20 | — | — | US | disclosed |
| US-20080004404-A1 | THERMOPLASTIC COMPOSITION HAVING IMPROVED SCRATCH RESISTANCE, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-01-03 | — | — | US | disclosed |