Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743135 | 0.90 | ADORA3 (0.46) | KDM4EHPGDLMNAADORA3SLC6A4 | |
| SCHEMBL14357634 | 0.89 | LMNA (0.57) | KDM4EHPGDLMNAADORA3SLC6A4 | |
| SCHEMBL12221853 | 0.89 | FAAH (0.48) | KDM4EGAAADORA3BACE1SLC6A4 | |
| SCHEMBL19194913 | 0.89 | KMT2A (0.51) | KDM4EHPGDLMNAADORA3BACE1 | |
| SCHEMBL12313794 | 0.89 | ADORA3 (0.48) | KDM4ELMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL23968910 | 0.89 | ESR2 (0.57) | KDM4EHPGDGAAADORA3BACE1 | |
| SCHEMBL11949421 | 0.89 | ADORA3 (0.48) | KDM4ELMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL13583422 | 0.88 | SLC6A4 (0.49) | KDM4EHPGDLMNAGAAADORA3 | |
| SCHEMBL12893202 | 0.88 | ACHE (0.56) | KDM4EHPGDADORA3BACE1ACHE | |
| SCHEMBL16775320 | 0.88 | SLC6A2 (0.51) | KDM4EHPGDLMNAGAAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9141006-B2 | Imaging member having improved imaging layers | XEROX CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| US-8623578-B2 | Tetraaryl polycarbonate containing photoconductors | XEROX CORPORATION (US) | 2014-01-07 | — | — | US | disclosed |
| US-8426092-B2 | Poly(imide-carbonate) polytetrafluoroethylene containing photoconductors | XEROX CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |