SCHEMBL1341309

SCHEMBL1341309

C=CCNNCCCCC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.42
TSHR P16473 6/20 0.42
ALDH1A1 P00352 3/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
EPHX1 P07099 6/20 0.39
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH7 P40394 2/20 0.39
ADH4 P08319 1/20 0.39
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15519857 1.00 FAAH (0.42) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL7648107 0.98 TSHR (0.46) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL28887822 0.98 TSHR (0.46) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL3796966 0.98 TSHR (0.46) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL25093190 0.98 TSHR (0.46) FAAHTSHRALDH1A1ZDHHC20ZDHHC2
SCHEMBL1083082 0.82
SCHEMBL88378 0.79 TSHR (0.62) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL6280918 0.78
SCHEMBL89641 0.78
SCHEMBL7535052 0.76 TSHR (0.55) FAAHTSHRALDH1A1ZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084932-B2 Phenylethynylnaphthalene dyes and methods for their use Sony Group Corporation (JP) 2021-08-10 US claimed
CN-1950341-A Naphthalimide derivatives for the treatment of cancer UNIBIOSCREEN SA (BE) 2007-04-18 CN claimed
US-6858608-B2 Chemical derivatives and their application as antitelomerase agents AVENTIS PHARMA S.A. (FR) 2005-02-22 US claimed
WO-2005011573-A2 NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS AUSPEX PHARMACEUTICALS, INC. (US) 2005-02-10 WO claimed
US-20030078263-A1 Chemical derivatives and their application as antitelomerase agents AVENTIS PHARMA SA (FR) 2003-04-24 US claimed
JP-2002518063-A 2002-06-25 JP claimed
EP-0778263-B1 BENZENE COMPOUND AND MEDICINAL USE THEREOF WELFIDE CORP (JP) 2002-01-09 EP claimed
US-6235936-B1 TRANSITION METAL CATALYST FOR ARYLATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-05-22 US claimed
EP-1088098-A2 FITNESS ASSAY AND ASSOCIATED METHODS UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND SOCIAL SERVICES (US) 2001-04-04 EP claimed
WO-1999067254-A2 MULTI-DRUG RESISTANT RETROVIRAL PROTEASE INHIBITORS AND USE THEREOF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-29 WO claimed
WO-1999067417-A2 FITNESS ASSAY AND ASSOCIATED METHODS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-29 WO claimed
EP-0682519-A4 ADENOSINE KINASE INHIBITORS. GENSIA INC (US) 1997-12-17 EP claimed
EP-0682519-A1 ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1995-11-22 EP claimed
WO-1994017803-A9 ADENOSINE KINASE INHIBITORS 1994-09-29 WO claimed
WO-1994017803-A1 ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1994-08-18 WO claimed
WO-1992012718-A1 ADENOSINE KINASE INHIBITORS GENSIA, INC. (US) 1992-08-06 WO claimed
EP-0094792-B1 7-OXABICYCLOHEPTANE SUBSTITUTED AMINO PROSTAGLANDIN ANALOGS E.R. Squibb & Sons, Inc. (US) 1988-11-17 EP claimed
EP-2673284-B1 NEW IRIDIUM-BASED COMPLEXES FOR ECL ROCHE DIAGNOSTICS GMBH (DE) 2017-08-30 EP disclosed
US-4663336-A ANTICOAGULANTS E. R. SQUIBB & SONS, INC. (US) 1987-05-05 US disclosed
EP-0207684-A2 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1987-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078263-A1 Chemical derivatives and their application as antitelomerase agents TERT, TERF2, DUT FAAH 4744/4885TSHR 3003/4885ALDH1A1 854/4885
US-11084932-B2 Phenylethynylnaphthalene dyes and methods for their use CENPE, NR2E3, RCN1 FAAH 3932/4885TSHR 115/4885ALDH1A1 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.