Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3317990 | 0.85 | RECQL (0.55) | MAPTRECQLTBXAS1LMNAKAT2B | |
| SCHEMBL10421950 | 0.81 | MAPT (0.56) | MAPTRECQLTBXAS1LMNAALDH1A1 | |
| SCHEMBL9042252 | 0.78 | ALDH1A1 (0.49) | MAPTRECQLLMNAALDH1A1CYP1A2 | |
| SCHEMBL10485371 | 0.77 | KAT2B (0.59) | TBXAS1LMNAKAT2BALDH1A1CYP1A2 | |
| SCHEMBL12877767 | 0.77 | LMNA (0.64) | MAPTRECQLTBXAS1LMNAKMT2A | |
| SCHEMBL24000681 | 0.77 | MAPT (0.48) | MAPTRECQLTBXAS1KAT2BALDH1A1 | |
| SCHEMBL13728276 | 0.76 | MAPT (0.56) | MAPTRECQLTBXAS1LMNAKAT2B | |
| SCHEMBL13829800 | 0.76 | MAPT (0.60) | MAPTRECQLTBXAS1LMNAKAT2B | |
| SCHEMBL13925891 | 0.73 | POLB (0.52) | MAPTLMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL17571640 | 0.72 | MAPT (0.52) | MAPTRECQLTBXAS1KAT2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105690-A1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105690-A1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | IAPP, RNASE1, CTSA | MAPT 3953/4885RECQL 1030/4885TBXAS1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.