Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042355 | 0.81 | CNR2 (0.60) | ALDH1A1CNR2CNR1P2RX4ACHE | |
| SCHEMBL9882815 | 0.79 | ALDH1A1 (0.53) | ALDH1A1P2RX4CYP2C19LMNAKDM4E | |
| SCHEMBL9043723 | 0.78 | ALDH1A1 (0.51) | ALDH1A1P2RX4CYP2C19LMNAKMT2A | |
| SCHEMBL13413651 | 0.78 | MAPT (0.54) | ALDH1A1CYP1A2CYP2C19LMNAKMT2A | |
| SCHEMBL9041922 | 0.78 | ALDH1A1 (0.51) | ALDH1A1P2RX4KMT2AKDM4EHPGD | |
| SCHEMBL9042446 | 0.75 | ALDH1A1 (0.49) | ALDH1A1CNR2P2RX4LMNAKMT2A | |
| SCHEMBL9041998 | 0.75 | ALDH1A1 (0.49) | ALDH1A1P2RX4KDM4EPDE4APDE4B | |
| SCHEMBL7299091 | 0.74 | TSHR (0.56) | ALDH1A1CNR2P2RX4CYP1A2LMNA | |
| SCHEMBL7305503 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CNR2P2RX4PDE4APDE4B | |
| SCHEMBL15833034 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |