Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145040 | 0.79 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL9293066 | 0.78 | KMT2A (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13313607 | 0.76 | CXCR2 (0.47) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL29115354 | 0.76 | KMT2A (0.47) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL10180000 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KIF11SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL9768982 | 0.72 | KMT2A (0.48) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL1886221 | 0.71 | MAPT (0.65) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL5786861 | 0.71 | SMN1; SMN2 (0.65) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL11685641 | 0.71 | LMNA (0.47) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 | |
| SCHEMBL5670628 | 0.71 | LMNA (0.47) | MEN1KMT2AALDH1A1KIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687665-B2 | 2-(4-Chlorophenyl)-N-[(1R,2R)-2-(benzyloxy)cyclohexyl]-2-methylpropanamide; modulators of 11- beta hydroxyl steroid dehydrogenase type 1 and/or mineralocorticoid receptor | INCYTE CORPORATION (US) | 2010-03-30 | — | — | US | disclosed |