Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417085 | 0.94 | TMPRSS15 (0.43) | TMPRSS15ACHEBCHEGAAMAPT | |
| SCHEMBL13416653 | 0.90 | ACHE (0.40) | ACHEBCHEMME | |
| SCHEMBL13417046 | 0.89 | NAALAD2 (0.44) | ACHEBCHEGAA | |
| SCHEMBL13416753 | 0.89 | BCHE (0.47) | ACHEBCHEMME | |
| SCHEMBL13416301 | 0.87 | FOLH1 (0.43) | ACHEBCHEMME | |
| SCHEMBL13416590 | 0.86 | TMPRSS15 (0.41) | TMPRSS15CASP1 | |
| SCHEMBL13416923 | 0.84 | PRSS1 (0.44) | ACHE | |
| SCHEMBL13416885 | 0.84 | FNTA (0.43) | — | |
| SCHEMBL13417070 | 0.84 | ACHE (0.46) | ACHEBCHE | |
| SCHEMBL13416575 | 0.83 | ACHE (0.39) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2010-04-22 | — | — | US | disclosed |
| WO-2008095841-A2 | NITRIC OXIDE DONOR COMPOUNDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099729-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | TMPRSS15 2014/4885ACHE 540/4885BCHE 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.