Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095520 | 0.93 | FTO (0.43) | FTOKDM4EMEN1MAPTBLM | |
| SCHEMBL3626595 | 0.93 | FTO (0.43) | FTOKDM4EMEN1MAPTBLM | |
| SCHEMBL9915064 | 0.93 | FTO (0.43) | FTOKDM4EMEN1MAPTBLM | |
| SCHEMBL16728234 | 0.92 | FTO (0.35) | FTOKDM4EMEN1MAPTBLM | |
| Hydrochloric Acid SCHEMBL9638604 | 0.92 | FTO (0.42) | FTOKDM4EMEN1MAPTBLM | |
| Hydrochloric Acid SCHEMBL12492233 | 0.92 | FTO (0.42) | FTOKDM4EMEN1MAPTBLM | |
| SCHEMBL13311374 | 0.91 | ABCB1 (0.44) | FTOKDM4EMEN1MAPTBLM | |
| Rhodamine 6G SCHEMBL10028465 | 0.90 | ABCB1 (0.38) | FTOKDM4EMEN1MAPTBLM | |
| SCHEMBL9637519 | 0.90 | FTO (0.43) | FTOKDM4EMEN1MAPTBLM | |
| Hydrochloric Acid SCHEMBL29460430 | 0.90 | USP2 (0.44) | FTOKDM4EMEN1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357569-A1 | CYCLOSPORIN CONJUGATES | UCL BUSINESS PLC (GB) | 2014-12-04 | — | — | US | disclosed |
| US-8766238-B2 | Polymeric anions/cations | MERCK PATENT GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100059740-A1 | POLYMERIC ANIONS/CATIONS | MERCK PATENT GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357569-A1 | CYCLOSPORIN CONJUGATES | CYP11B1, SHMT2, MRM1 | FTO 2192/4885KDM4E 2905/4885MEN1 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.