SCHEMBL9915064

SCHEMBL9915064

CC/N=c1/cc2oc3cc(NCC)c(C)cc3c(-c3ccccc3C(=O)O)c-2cc1C

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 2/20 0.43
▸ KDM4E B2RXH2 5/20 0.41
▸ POLB P06746 3/20 0.41
▸ MAPT P10636 4/20 0.41
▸ USP2 O75604 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ BLM P54132 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ HPGD P15428 3/20 0.41
▸ THRB P10828 2/20 0.41
▸ RECQL P46063 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ CASP1 P29466 2/20 0.41
▸ CASP7 P55210 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ BRCA1 P38398 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ MYC P01106 1/20 0.36
▸ ABCB1 P08183 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1095520 1.00 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
SCHEMBL3626595 1.00 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
Hydrochloric Acid SCHEMBL9638604 0.99 FTO (0.42) FTOKDM4EPOLBMAPTUSP2
Hydrochloric Acid SCHEMBL12492233 0.99 FTO (0.42) FTOKDM4EPOLBMAPTUSP2
SCHEMBL9637519 0.97 FTO (0.43) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL5605513 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL29579793 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Perchlorate SCHEMBL5605515 0.96 FTO (0.40) FTOKDM4EPOLBMAPTUSP2
Rhodamine 6G SCHEMBL7454756 0.93 FTO (0.39) FTOKDM4EPOLBMAPTUSP2
SCHEMBL13428306 0.93 FTO (0.35) FTOKDM4EPOLBMAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3249049-B1 COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE SUCCINYL OR METHYL SUCCINYL GROUPS FROM EPSILON AMINO LYSINE MOIETIES ENZO LIFE SCIENCES INC (US) 2020-03-04 — — EP disclosed
EP-2686680-B1 FLUORESCENT DYES, FLUORESCENT DYE KITS, AND METHODS OF PREPARING LABELED MOLECULES BIOTIUM INC (US) 2018-06-13 — — EP disclosed
US-20180156810-A1 FLUORESCENT COMPOUNDS BIOTIUM, INC. 2018-06-07 — — US disclosed
US-20180143113-A1 Fluorescent Dyes, Fluorescent Dye Kits, and Methods of Preparing Labeled Molecules BIOTIUM, INC. 2018-05-24 — — US disclosed
US-9814781-B2 Environmentally sensitive compositions and methods of use thereof RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (STATUTORY SUCCESSOR TO RHODE ISLAND BOARD OF GOVERNORS FOR HIGHER EDUCATION) (US) 2017-11-14 — — US disclosed
US-9791450-B2 Fluorescent compounds BIOTIUM, INC. (US) 2017-10-17 — — US disclosed
US-9791450-B2 Fluorescent compounds BIOTIUM, INC. (US) 2017-10-17 — — US disclosed
EP-2663648-B1 COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE SUCCINYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES ENZO LIFE SCIENCES INC (US) 2017-07-12 — — EP disclosed
US-20170137863-A1 Self-Immolative Probes for Enzyme Activity Detection ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) 2017-05-18 — — US disclosed
US-9637773-B2 Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties ENZO LIFE SCIENCES, INC. (US) 2017-05-02 — — US disclosed
US-8084175-B2 Electrophotographic toner set KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-12-27 — — US disclosed
US-20100162494-A1 FUNCTIONALIZED NANOPARTICLES CIBA CORPORATION (US) 2010-07-01 — — US disclosed
US-20090305410-A1 FLUORESCENT COMPOUNDS BIOTIUM, INC. (US) 2009-12-10 — — US disclosed
US-20090303461-A1 DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) SUN LEI 2009-12-10 — — US disclosed
US-20090291378-A1 ELECTROPHOTOGRAPHIC TONER SET KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-11-26 — — US disclosed
US-7485471-B1 Seed particles of silver, gold, and/or copper for catalyzing surface enhanced Raman scattering (SERS) substrate; specific binding members have no Raman labels attached; bound capture reagent hasRaman label, and a bound target analyte; complexing DNA, RNA, polypeptides, antibodies, antigens, polypeptides INTEL CORPORATION (US) 2009-02-03 — — US disclosed
US-20090023135-A1 DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY INTEL CORPORATION 2009-01-22 — — US disclosed
US-20080214811-A1 XANTHENE DYES BIOSEARCH TECHNOLOGIES, INC. (US) 2008-09-04 — — US disclosed
US-7344701-B2 Xanthene dyes BIOSEARCH TECHNOLOGIES, INC. (US) 2008-03-18 — — US disclosed
US-20070042295-A1 Optical data carrier comprising a polymeric network in the information layer LANXESS DEUTSCHLAND GMBH (DE) 2007-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090303461-A1 DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) FABP1, FABP3, FABP2 FTO 1817/4885KDM4E 4823/4885POLB 828/4885
US-20180143113-A1 Fluorescent Dyes, Fluorescent Dye Kits, and Methods of Preparing Labeled Molecules HLCS, RAB5IF, PFDN6 FTO 2268/4885KDM4E 4018/4885POLB 1568/4885
US-20100162494-A1 FUNCTIONALIZED NANOPARTICLES TYR, ZKSCAN2, TST FTO 43/4885KDM4E 1593/4885POLB 2232/4885
US-20090305410-A1 FLUORESCENT COMPOUNDS MKI67, CD68, CA5B FTO 1806/4885KDM4E 2767/4885POLB 1267/4885
US-20170137863-A1 Self-Immolative Probes for Enzyme Activity Detection MGAM, SI, ENGASE FTO 2054/4885KDM4E 4268/4885POLB 1748/4885
US-20080214811-A1 XANTHENE DYES ANXA5, ANTXR2, XPOT FTO 2025/4885KDM4E 3630/4885POLB 3782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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