SCHEMBL1343014

SCHEMBL1343014

O=C1NSNc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRA P16234 1/20 0.50
FER P16591 1/20 0.50
LTK P29376 1/20 0.50
CDK8 P49336 1/20 0.50
ACVR1 Q04771 1/20 0.50
LRRK2 Q5S007 1/20 0.50
DYRK1B Q9Y463 1/20 0.50
PDE7A Q13946 1/20 0.45
PDE7B Q9NP56 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TNKS2 Q9H2K2 6/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GSK3B P49841 1/20 0.42
ALDH1A1 P00352 6/20 0.41
KDM4E B2RXH2 5/20 0.41
HPGD P15428 4/20 0.41
HSD17B10 Q99714 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KMT2A Q03164 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272340 0.74
SCHEMBL29412546 0.71 PDGFRA (0.44) PDGFRAFERLTKCDK8ACVR1
SCHEMBL2420711 0.70 LRRK2 (0.90) PDGFRAFERLTKCDK8ACVR1
SCHEMBL366728 0.70
SCHEMBL11209885 0.67 CYP1A2 (0.51) TNKS2ALDH1A1HSD17B10SMN1; SMN2KMT2A
SCHEMBL11530505 0.67 TDP1 (0.41) FERGSK3BALDH1A1KDM4EHSD17B10
SCHEMBL2551621 0.67 MAOA (0.39) PDGFRAFERLTKCDK8ACVR1
SCHEMBL3354373 0.65 MAOA (0.38) PDGFRAFERLTKCDK8ACVR1
Hydrochloric Acid SCHEMBL6299954 0.65 LRRK2 (0.95) PDGFRAFERLTKCDK8ACVR1
SCHEMBL3907736 0.65 PDGFRA (0.52) PDGFRAFERLTKCDK8ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100184749-A1 BENZOTHIADIAZINE COMPOUNDS AND THEIR USE EPIX Delaware ,Inc. (US) 2010-07-22 US claimed
WO-2008045558-A2 BENZOTHIADIAZINE COMPOUNDS AND THEIR USE EPIX DELAWARE, INC. (US) 2008-04-17 WO claimed
EP-0063866-B1 QUINOLIN-3-YLOXY(AMINO)PHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1987-12-09 EP claimed
EP-0029319-B1 QUINOLINYLOXY(AMINO)PHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1986-01-15 EP claimed
EP-0004414-B1 MIXTURES OF HERBICIDAL PYRIDYLOXYPHENOXYPROPANOIC ACID DERIVATIVES WITH OTHER HERBICIDES, AND PROCESSES OF KILLING UNWANTED PLANTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-24 EP claimed
EP-0023785-B1 QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1985-04-03 EP claimed
EP-0027915-B1 HERBICIDAL AGENTS BASED ON DIPHENYL ETHERS AND BENZOTHIADIAZINONE DIOXIDES OR PYRIDINOTHIADIAZINONE DIOXIDES, AND THEIR USE BASF Aktiengesellschaft (DE) 1983-05-18 EP claimed
EP-0008368-B1 METHOD FOR PREPARING CYANO COMPOUNDS BASF Aktiengesellschaft (DE) 1980-11-12 EP claimed
US-12325646-B2 Fertigation water treatment UNIVERSITY OF GUELPH (CA) 2025-06-10 US disclosed
US-20220234916-A1 WATER TREATMENT UNIVERSITY OF GUELPH (CA) 2022-07-28 US disclosed
CN-106719718-A A kind of Herbicidal combinations containing dichloroquinoline humulone 安徽省农业科学院植物保护与农产品质量安全研究所 2017-05-31 CN disclosed
CN-104768381-A Herbicidal compositions comprising aminopyralid and bentazon DOW AGROSCIENCES LLC 2015-07-08 CN disclosed
CN-103907629-A Compound herbicide for preventing and removing ligularia virgaurea as well as preparation method and application method thereof QINGHAI ACADEMY OF ANIMAL SCIENCE AND VETERINARY MEDICINE 2014-07-09 CN disclosed
CN-103875686-A Penoxsulam-containing herbicide composition DOW AGROSCIENCES LLC 2014-06-25 CN disclosed
WO-2007089335-A2 MULTICYCLIC AMINO ACID DERIVATIVES AND METHODS OF THEIR USE LEXICON PHARMACEUTICAL INC. (US) 2007-08-09 WO disclosed
US-6486096-B1 Herbicidal compositions with acylated aminophenylsulfonylureas HOECHST SCHERING AGREVO GMBH (DE) 2002-11-26 US disclosed
US-4208514-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1980-06-17 US disclosed
US-4200743-A Preparation of 1-cyano-2,1,3-benzothiadiazinones BASF AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
US-4139700-A ACID-CATALYZED CYCLIZATION OF SULFAMOYL ACID OR ESTER MONSANTO COMPANY (US) 1979-02-13 US disclosed
US-4054440-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184749-A1 BENZOTHIADIAZINE COMPOUNDS AND THEIR USE CCR2, CCR5, CCR1 PDGFRA 256/4885FER 1549/4885LTK 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.