SCHEMBL13432011

SCHEMBL13432011

Cc1[nH]c(C=O)c(C)c1C(=O)OC1C(C)CC(C)CC1C

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
GRM1 Q13255 2/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.33
HPGD P15428 1/20 0.32
ABL1 P00519 1/20 0.31
RET P07949 1/20 0.31
PDGFRB P09619 1/20 0.31
FGFR1 P11362 1/20 0.31
FLT3 P36888 1/20 0.31
ALK Q9UM73 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9888933 0.84 ALDH1A1 (0.30) NPSR1ALDH1A1KMT2APOLB
SCHEMBL14226070 0.81 NPSR1 (0.38) RAB9ASMN1; SMN2NPC1NPSR1ALDH1A1
SCHEMBL15331397 0.72 ALDH1A1 (0.58) RAB9ASMN1; SMN2NPC1NPSR1ALDH1A1
SCHEMBL13380256 0.72 MEN1 (0.40) RAB9ANPSR1KMT2AGAAMAPT
SCHEMBL13432010 0.71 NOTUM (0.45) SMN1; SMN2
SCHEMBL1627475 0.69 ALDH1A1 (0.66) RAB9ASMN1; SMN2NPC1ALDH1A1KMT2A
SCHEMBL9913929 0.68
SCHEMBL13303521 0.68 ALDH1A1 (0.39) RAB9ASMN1; SMN2NPSR1ALDH1A1KMT2A
SCHEMBL13432017 0.67 PDE4D (0.36)
SCHEMBL13380257 0.67 NOTUM (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334085-B2 Colored curable composition, color filter and method of producing the same, and dipyrromethene metal complex compound and tautomer thereof FUJIFILM CORPORATION (JP) 2012-12-18 US disclosed
US-20120315579-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2012-12-13 US disclosed
US-20100055582-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055582-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF MAPT, UACA, HELZ RAB9A 2661/4885SMN1; SMN2 2598/4885NPC1 4182/4885
US-20120315579-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF PRODUCING THE SAME, AND DIPYRROMETHENE METAL COMPLEX COMPOUND AND TAUTOMER THEREOF MAPT, UACA, HELZ RAB9A 2661/4885SMN1; SMN2 2598/4885NPC1 4182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.