SCHEMBL13380256

SCHEMBL13380256

Cc1c(C=O)[nH]c(NC(=O)c2cccc(C(F)(F)F)c2)c1C(=O)OC1C(C)CC(C)CC1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
KCNK3 O14649 2/20 0.40
KCNK9 Q9NPC2 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
P2RX1 P51575 1/20 0.39
LMNA P02545 1/20 0.39
KCNQ3 O43525 2/20 0.38
KCNQ2 O43526 2/20 0.38
KCNE1 P15382 2/20 0.38
KCNQ1 P51787 2/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
CCNA1 P78396 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13380249 0.89 ALDH1A1 (0.41) MEN1KMT2AGAAHTTRAB9A
SCHEMBL13380259 0.85 TAS1R3 (0.36) MEN1KMT2AGAAHTTRAB9A
SCHEMBL13380260 0.82 GAA (0.45) MEN1KMT2AGAAHTTRAB9A
SCHEMBL13380264 0.78 ALDH1A1 (0.48) MEN1KMT2AGAAHTTRAB9A
SCHEMBL28637086 0.65 CES2 (0.54) MEN1KMT2AGAATAS1R3TAS1R1
SCHEMBL12212489 0.63 MEN1 (0.65) MEN1KMT2AGAAHTTRAB9A
SCHEMBL28968096 0.62 ALDH1A1 (0.56) MEN1KMT2AGAATAS1R3TAS1R1
SCHEMBL22410569 0.61 CES2 (0.51) MEN1KMT2ARAB9ATAS1R3TAS1R1
SCHEMBL27052578 0.60 CES2 (0.48) MEN1KMT2ATAS1R3TAS1R1TAS1R2
SCHEMBL28342942 0.60 HPGD (0.52) MEN1KMT2ATAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343696-B2 Colored curable composition, fluorine-containing dipyrromethene compound and tautomer thereof, and fluorine-containing dipyrromethene metal complex and tautomer thereof, and color filter using the same and method for producing the color filter FUJIFILM CORPORATION (JP) 2013-01-01 US disclosed
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081071-A1 COLORED CURABLE COMPOSITION, FLUORINE-CONTAINING DIPYRROMETHENE COMPOUND AND TAUTOMER THEREOF, AND FLUORINE-CONTAINING DIPYRROMETHENE METAL COMPLEX AND TAUTOMER THEREOF, AND COLOR FILTER USING THE SAME AND METHOD FOR PRODUCING THE COLOR FILTER SCO2, TDO2, FTH1 MEN1 918/4885KMT2A 2202/4885GAA 4767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.