SCHEMBL1627475

SCHEMBL1627475

CCOC(=O)c1c(C)[nH]c(C=O)c1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.66
KMT2A Q03164 4/20 0.66
POLB P06746 1/20 0.66
HPGD P15428 3/20 0.64
SMN1; SMN2 Q16637 4/20 0.62
MAPK1 P28482 1/20 0.60
MAPT P10636 4/20 0.54
KDM4E B2RXH2 3/20 0.54
GLA P06280 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
LMNA P02545 2/20 0.53
ABL1 P00519 1/20 0.52
RET P07949 1/20 0.52
PDGFRB P09619 1/20 0.52
FGFR1 P11362 1/20 0.52
FLT3 P36888 1/20 0.52
ALK Q9UM73 1/20 0.52
MEN1 O00255 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7008915 0.88 ALDH1A1 (0.73) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL1077379 0.86 ALDH1A1 (0.62) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25299252 0.85 ALDH1A1 (0.60) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25256791 0.85 ALDH1A1 (0.60) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25294630 0.85 ALDH1A1 (0.60) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25258780 0.84 SMN1; SMN2 (0.60) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL15132785 0.83 HPGD (0.57) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25258308 0.83 ALDH1A1 (0.48) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25258164 0.83 SMN1; SMN2 (0.58) ALDH1A1KMT2APOLBHPGDSMN1; SMN2
SCHEMBL25294601 0.83 SMN1; SMN2 (0.58) ALDH1A1KMT2APOLBHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118110-A Preparation of bromine-containing seven-membered boron fluoride compound and application of bromine-containing seven-membered boron fluoride compound in fluorescent ink 三峡大学 2025-06-10 CN claimed
CN-117362615-A Modified alkyd resin and varnish composition containing modified alkyd resin 西北永新涂料有限公司 2024-01-09 CN claimed
US-20260049217-A1 DYED ARTICLES FOR VISIBLE LIGHT FILTERING OAKLEY, INC. (US) 2026-02-19 US disclosed
US-20260049192-A1 DYED ARTICLES FOR VISIBLE AND INFRARED LIGHT ABSORPTION OAKLEY, INC. (US) 2026-02-19 US disclosed
US-20260043944-A1 OPTICAL FILM, DISPLAY DEVICE, AND ULTRAVIOLET ABSORBING LAYER FORMING COMPOSITION TOPPAN HOLDINGS INC. (JP) 2026-02-12 US disclosed
WO-2025233641-A1 NOVEL PHOTOINDUCIBLE KINASE INHIBITORS FOR TREATING PROLIFERATIVE AND VASOPROLIFERATIVE DISEASES SEMMELWEIS EGYETEM (HU) 2025-11-13 WO disclosed
CN-120271615-A BF-containing2Preparation method of seven-membered boron fluoride compound and application of seven-membered boron fluoride compound in fluorescent anti-counterfeiting film 三峡大学 2025-07-08 CN disclosed
CN-120118110-A Preparation of bromine-containing seven-membered boron fluoride compound and application of bromine-containing seven-membered boron fluoride compound in fluorescent ink 三峡大学 2025-06-10 CN disclosed
CN-120118110-A Preparation of bromine-containing seven-membered boron fluoride compound and application of bromine-containing seven-membered boron fluoride compound in fluorescent ink 三峡大学 2025-06-10 CN disclosed
US-20250172723-A1 OPTICAL FILM AND DISPLAY DEVICE TOPPAN HOLDINGS INC. (JP) 2025-05-29 US disclosed
US-20250089549-A1 OPTICAL FILM, COMPOSITION FOR FORMING COLORED LAYER, DIPYRROMETHENE COBALT COMPLEX AND DISPLAY DEVICE TOPPAN HOLDINGS INC. (JP) 2025-03-13 US disclosed
EP-0934931-A2 3-Benzylidene-2-indolinones and their analogues as tyrosine kinase activity modulators Sugen, Inc. (US) 1999-08-11 EP disclosed
US-5886020-A MODULATING TYROSINE KINASE SIGNAL TRANSDUCTION IN ORDER TO REGULATE OR INHIBIT ABNORMAL CELL PROLIFERATION SUGEN, INC. (US) 1999-03-23 US disclosed
US-5883113-A TYROSINE KINASE INHIBITORS; ANTIPROLIFERATIVE AND ANTICARCINOGENIC AGENTS; DIABETES, ARTHRITIS, RESTENOSIS, ATHEROSCLEROSIS SUGEN, INC. (US) 1999-03-16 US disclosed
US-5883116-A ANTITUMOR AGENTS AND ENZYME INHIBITORS SUGEN, INC. (US) 1999-03-16 US disclosed
US-5834504-A MODULATING, INHIBITING ABNORMAL CELL PROLIFERATION; ENZYME INHIBITION SUGEN, INC. (US) 1998-11-10 US disclosed
EP-0769947-A4 INDOLINONE COMPOUNDS FOR THE TREATMENT OF DISEASE SUGEN INC (US) 1998-09-30 EP disclosed
US-5792783-A CAPABLE OF MODULATING TYROSINE KINASE SIGNAL TRANSDUCTION IN ORDER TO REGULATE, MODULATE AND/OR INHIBIT ABNORMAL CELL PROLIFERATION SUGEN, INC. (US) 1998-08-11 US disclosed
EP-0769947-A1 INDOLINONE COMPOUNDS FOR THE TREATMENT OF DISEASE Sugen, Inc. (US) 1997-05-02 EP disclosed
WO-1996040116-A1 INDOLINONE COMPOUNDS FOR THE TREATMENT OF DISEASE SUGEN, INC. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043944-A1 OPTICAL FILM, DISPLAY DEVICE, AND ULTRAVIOLET ABSORBING LAYER FORMING COMPOSITION KDM5A, VCL, KDM5B ALDH1A1 211/4885KMT2A 286/4885POLB 3032/4885
US-20260049217-A1 DYED ARTICLES FOR VISIBLE LIGHT FILTERING LBR, CRY2, CORO1C ALDH1A1 845/4885KMT2A 3902/4885POLB 3574/4885
US-20260049192-A1 DYED ARTICLES FOR VISIBLE AND INFRARED LIGHT ABSORPTION CRY1, CRY2, CLIC1 ALDH1A1 319/4885KMT2A 3787/4885POLB 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.