SCHEMBL13435401

SCHEMBL13435401

CC(=O)C[C@H]1CN(C)CC(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 2/20 0.36
ITGA5 P08648 2/20 0.36
ITGB3 P05106 1/20 0.36
ITGB2 P05107 1/20 0.36
ITGAV P06756 1/20 0.36
ITGA2B P08514 1/20 0.36
ITGB5 P18084 1/20 0.36
ITGAL P20701 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21455159 0.79 PRKCD (0.40) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL27326163 0.79 PRKCD (0.40) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL21455300 0.79 PRKCD (0.40) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL13435368 0.74 ITGB3 (0.31) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL12572124 0.74 ITGB3 (0.31) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL13435367 0.74 ITGB3 (0.31) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL11062751 0.72
SCHEMBL10709560 0.72 ITGB1 (0.39) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL24928556 0.70 CAD (0.40) ITGB1ITGA5ITGB3ITGB2ITGAV
SCHEMBL23260109 0.70 CAD (0.40) ITGB1ITGA5ITGB3ITGB2ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA ITGB1 4228/4885ITGA5 3072/4885ITGB3 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.