Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190722 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1BCHEACHE | |
| SCHEMBL2190718 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1BCHEACHE | |
| SCHEMBL13912776 | 0.82 | MEN1 (0.65) | MEN1KMT2ABCHEACHE | |
| SCHEMBL13435489 | 0.79 | MEN1 (0.70) | MEN1KMT2ABCHEMAOBRAB9A | |
| SCHEMBL13849463 | 0.76 | ALDH1A1 (0.62) | ALDH1A1CA12CA7CA9CA14 | |
| Ethyl Cinnamate SCHEMBL112446 | 0.75 | CA12 (0.72) | MEN1KMT2AALDH1A1CA12CA7 | |
| Ethyl Cinnamate SCHEMBL12001792 | 0.75 | CA12 (0.72) | MEN1KMT2AALDH1A1CA12CA7 | |
| Ethyl Cinnamate SCHEMBL112445 | 0.75 | CA12 (0.72) | MEN1KMT2AALDH1A1CA12CA7 | |
| Ethyl Cinnamate SCHEMBL1866942 | 0.75 | CA12 (0.72) | MEN1KMT2AALDH1A1CA12CA7 | |
| SCHEMBL29849080 | 0.74 | MAPT (0.51) | MEN1KMT2AALDH1A1LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671087-B2 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof | SEPRACOR INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671087-B2 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof | SEPRACOR INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20090163593-A1 | AMINES THAT INHIBIT A MAMMALIAN ANANDAMIDE TRANSPORTER, AND METHODS OF USE THEREOF | AQUILA BRIAN M | 2009-06-25 | — | — | US | disclosed |
| US-20090163593-A1 | AMINES THAT INHIBIT A MAMMALIAN ANANDAMIDE TRANSPORTER, AND METHODS OF USE THEREOF | AQUILA BRIAN M | 2009-06-25 | — | — | US | disclosed |
| US-7511073-B2 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof | SEPRACOR, INC. (US) | 2009-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163593-A1 | AMINES THAT INHIBIT A MAMMALIAN ANANDAMIDE TRANSPORTER, AND METHODS OF USE THEREOF | SLC6A2, HTR2A, SLC18A1 | MEN1 917/4885KMT2A 771/4885ALDH1A1 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.