Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908387 | 0.91 | ALDH1A1 (0.65) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL7908382 | 0.91 | ALDH1A1 (0.65) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL13809174 | 0.87 | ACHE (0.51) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL11313343 | 0.83 | MAOB (0.49) | ALDH1A1LMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7908625 | 0.83 | BCHE (0.64) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL7908622 | 0.83 | BCHE (0.64) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL7915320 | 0.82 | BCHE (0.65) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL7915317 | 0.82 | BCHE (0.65) | ALDH1A1AKR1B10AKR1B1LMNAKDM4E | |
| SCHEMBL7915261 | 0.81 | BCHE (0.65) | ALDH1A1AKR1B10AKR1B1KDM4EHPGD | |
| SCHEMBL7916463 | 0.81 | BCHE (0.65) | ALDH1A1AKR1B10AKR1B1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | CERNOFINA, LLC | 2009-05-14 | — | — | US | disclosed |
| US-20090016990-A1 | Antimicrobial Compositions | CUTLER, ELIOT | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | SELP, SELE, SELPLG | ALDH1A1 1723/4885AKR1B10 2884/4885AKR1B1 2281/4885 |
| US-20090016990-A1 | Antimicrobial Compositions | C5, TLR1, PRF1 | ALDH1A1 791/4885AKR1B10 531/4885AKR1B1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.