Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435290 | 0.87 | MAPT (0.41) | ADRB2ADRB3BACE1ADRB1MAPT | |
| SCHEMBL31076394 | 0.83 | MAPT (0.59) | ADRB2BACE1ADRB1ADRA1DMAPT | |
| SCHEMBL6815570 | 0.83 | MAPT (0.59) | ADRB2BACE1ADRB1ADRA1DMAPT | |
| SCHEMBL14547742 | 0.81 | PKM (0.47) | ADRB2PKMADRB3BACE1MAPT | |
| Sulfuric Acid SCHEMBL11881313 | 0.80 | ADRB2 (0.55) | ADRB2ADRB3ADRB1ADORA3CHRM1 | |
| SCHEMBL20285903 | 0.78 | MAPT (0.68) | ADRB2PKMBACE1MAPTHIF1A | |
| SCHEMBL10559921 | 0.76 | ADRB2 (0.74) | ADRB2ADRB3ADRB1ADRA1DTP53 | |
| SCHEMBL9971238 | 0.75 | ALOX5 (0.42) | ADRB2MAPTHIF1AHSD17B10TP53 | |
| SCHEMBL1548853 | 0.75 | ALOX5 (0.60) | TSHRNFKB1MAPK1ALDH1A1LMNA | |
| SCHEMBL10450798 | 0.75 | KDM4E (0.65) | ADRB2PKMBACE1ADRA1DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | Biovali Laboratories International (Barbados) S.R.L. (BB) | 2010-04-08 | — | — | US | disclosed |
| WO-2010026436-A2 | PHARMACEUTICAL COMPOUNDS | BIOVAIL LABORATORIES INTERNATIONAL (BARBADOS) SRL (BB) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | UGT2B7, CYP3A7, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ADRB2 91/4885PKM 2022/4885ADRB3 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.