Sugi Predict

Sugi Predict / Compounds / SCHEMBL6815570

SCHEMBL6815570

SCHEMBL6815570

O=CNCCc1ccc(O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.59
▸ MAPK1 P28482 5/20 0.59
▸ HIF1A Q16665 4/20 0.59
▸ HSD17B10 Q99714 4/20 0.59
▸ ALOX15 P16050 3/20 0.59
▸ THPO P40225 3/20 0.59
▸ TP53 P04637 2/20 0.59
▸ CYP1A2 P05177 2/20 0.59
▸ TSHR P16473 2/20 0.59
▸ NFKB1 P19838 2/20 0.59
▸ KDM4E B2RXH2 7/20 0.58
▸ LMNA P02545 5/20 0.58
▸ ALDH1A1 P00352 4/20 0.58
▸ BLM P54132 3/20 0.58
▸ PMP22 Q01453 3/20 0.58
▸ HPGD P15428 2/20 0.58
▸ GFER P55789 2/20 0.58
▸ GMNN O75496 2/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31076394 1.00 MAPT (0.59) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL10824528 0.88 ALOX15 (0.63) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL13435290 0.83 MAPT (0.41) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL13435519 0.83 ADRB2 (0.50) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL11806768 0.82 DRD1 (0.71) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL30088530 0.82 DRD1 (0.71) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL28207519 0.81 MAPT (0.59) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL9090253 0.81 ARG1 (0.53) MAPTHIF1AHSD17B10ALOX15THPO
SCHEMBL9971238 0.80 ALOX5 (0.42) MAPTMAPK1HIF1AHSD17B10ALOX15
SCHEMBL1936524 0.80 CYP1A2 (0.58) ALOX15CYP1A2TSHRNFKB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226519-A1 Metal Chelating Functional Graphene Materials CARNEGIE MELLON UNIVERSITY 2023-07-20 — — US claimed
US-11505549-B2 Process for preparation of Deutetrabenazine ALAPARTHI, Lakshmi Prasad (IN) 2022-11-22 — — US claimed
US-20210047317-A1 A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE ALAPARTHI, Lakshmi Prasad (IN) 2021-02-18 — — US claimed
WO-2019150387-A1 A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE ALAPARTHI LAKSHMI PRASAD (IN) 2019-08-08 — — WO claimed
US-12077487-B2 Methods of manufacturing benzoquinoline compounds AUSPEX PHARMACEUTICALS, INC. (US) 2024-09-03 — — US disclosed
US-20230226519-A1 Metal Chelating Functional Graphene Materials CARNEGIE MELLON UNIVERSITY 2023-07-20 — — US disclosed
US-20230060294-A1 METHODS OF MANUFACTURING BENZOQUINOLINE COMPOUNDS AUSPEX PHARMACEUTICALS LLC 2023-03-02 — — US disclosed
US-11505549-B2 Process for preparation of Deutetrabenazine ALAPARTHI, Lakshmi Prasad (IN) 2022-11-22 — — US disclosed
US-11505549-B2 Process for preparation of Deutetrabenazine ALAPARTHI, Lakshmi Prasad (IN) 2022-11-22 — — US disclosed
US-11505549-B2 Process for preparation of Deutetrabenazine ALAPARTHI, Lakshmi Prasad (IN) 2022-11-22 — — US disclosed
US-20210047317-A1 A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE ALAPARTHI, Lakshmi Prasad (IN) 2021-02-18 — — US disclosed
US-20210047317-A1 A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE ALAPARTHI, Lakshmi Prasad (IN) 2021-02-18 — — US disclosed
EP-1140799-B1 NOVEL PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-02 — — EP disclosed
US-6469005-B1 CONTROLLING AND PROTECTING AGAINST PHYTOPATHOGENIC MICROORGANISMS SYNGENTA PARTICIPATIONS AG (CH) 2002-10-22 — — US disclosed
EP-1140799-A1 NOVEL PROPARGYLETHER DERIVATIVES Syngenta Participations AG (CH) 2001-10-10 — — EP disclosed
WO-2000041998-A1 NOVEL PROPARGYLETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2000-07-20 — — WO disclosed
EP-0440887-B1 Improvement in the total synthesis of Erbstatin analogs ERBA CARLO SPA (IT) 1994-01-26 — — EP disclosed
US-5130472-A TOTAL SYNTHESIS OF ERBSTATIN ANALOGS FARMITALIA CARLO ERBA S.R.L. (IT) 1992-07-14 — — US disclosed
EP-0440887-A1 Improvement in the total synthesis of Erbstatin analogs FARMITALIA CARLO ERBA S.r.l. (IT) 1991-08-14 — — EP disclosed
US-4203898-A ANTICARCINOGENIC ELI LILLY AND COMPANY (US) 1980-05-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11505549-B2 Process for preparation of Deutetrabenazine CYP4X1, DRD4, CHRM5 MAPT 4447/4885MAPK1 2301/4885HIF1A 3130/4885
US-12077487-B2 Methods of manufacturing benzoquinoline compounds SLC18A2, SLC18A1, SLC6A2 MAPT 447/4885MAPK1 3556/4885HIF1A 3263/4885
US-20210047317-A1 A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE DRD4, DDO, CYP4X1 MAPT 4443/4885MAPK1 2252/4885HIF1A 3060/4885
US-20230060294-A1 METHODS OF MANUFACTURING BENZOQUINOLINE COMPOUNDS SLC18A2, SLC18A1, SLC6A2 MAPT 447/4885MAPK1 3556/4885HIF1A 3263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.