Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524444 | 0.96 | ALDH1A1 (0.59) | ALDH1A1THRBHPGDSMN1; SMN2GAA | |
| SCHEMBL14382722 | 0.87 | ALDH1A1 (0.51) | ALDH1A1THRBHPGDSMN1; SMN2GAA | |
| SCHEMBL7978191 | 0.85 | THRB (0.51) | ALDH1A1THRBHPGDMEN1KMT2A | |
| SCHEMBL13439737 | 0.79 | MEN1 (0.44) | ALDH1A1THRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3109453 | 0.72 | ROCK1 (0.75) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3571411 | 0.72 | RAB9A (0.54) | HPGDSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL13406702 | 0.72 | MCHR1 (0.54) | SMN1; SMN2GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL3031481 | 0.71 | CYP1A2 (0.58) | ALDH1A1SMN1; SMN2PRCPMEN1KMT2A | |
| SCHEMBL7067333 | 0.70 | CHRM4 (0.36) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7067885 | 0.70 | EGLN1 (0.44) | HPGDSMN1; SMN2GAALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696355-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2010-04-13 | — | — | US | disclosed |
| EP-2145540-A1 | Isothiazol carboxylic acid amides and their use in the protection of plants | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| EP-2145539-A1 | Isothiazolecarbamide derivatives for crop protection | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| EP-2132988-A1 | Isothiazole carboxylic acid amides and their use in the protection of plants | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |