Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524444 | 0.89 | ALDH1A1 (0.59) | THRBALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL14382722 | 0.88 | ALDH1A1 (0.51) | THRBALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL13439656 | 0.85 | ALDH1A1 (0.55) | THRBALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL7067325 | 0.80 | ALDH1A1 (0.47) | THRBALDH1A1LMNAHPGDTSHR | |
| SCHEMBL13439737 | 0.79 | MEN1 (0.44) | THRBALDH1A1LMNAROCK2RPS6KA5 | |
| SCHEMBL7975269 | 0.77 | LIPG (0.42) | THRBALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9423020 | 0.74 | HDAC1 (0.61) | THRBHDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL11543815 | 0.73 | LMNA (0.61) | HDAC3HDAC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL7067333 | 0.72 | CHRM4 (0.36) | ALDH1A1KDM4ELMNAHPGDRECQL | |
| SCHEMBL7067663 | 0.70 | TAS1R3 (0.42) | THRBALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064644-A1 | DICHLOROPYRIDYL- AND DICHLOROISOTHIAZOLYL-THIOCARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-07 | — | — | WO | disclosed |