Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524444 | 0.82 | ALDH1A1 (0.59) | MEN1KMT2ATHRBLMNAPTGER4 | |
| SCHEMBL7978191 | 0.79 | THRB (0.51) | MEN1KMT2ATHRBROCK1ROCK2 | |
| SCHEMBL13439656 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2ATHRBROCK1ROCK2 | |
| SCHEMBL13406703 | 0.76 | FDFT1 (0.52) | HTTSMN1; SMN2 | |
| SCHEMBL14382722 | 0.74 | ALDH1A1 (0.51) | MEN1KMT2ATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL8222905 | 0.72 | LMNA (0.48) | MEN1KMT2ACYP2D6ACACBLMNA | |
| SCHEMBL13524538 | 0.70 | LTA4H (0.53) | MEN1KMT2APOLBCYP2D6LMNA | |
| SCHEMBL11833855 | 0.69 | PTGS1 (0.80) | MEN1KMT2ACYP3A4CYP2D6MAPK1 | |
| SCHEMBL10338889 | 0.69 | UTS2R (0.64) | MEN1KMT2AROCK1ROCK2PRKG1 | |
| SCHEMBL5315212 | 0.69 | PTGS1 (0.51) | MEN1KMT2ACYP2D6LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696355-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2010-04-13 | — | — | US | disclosed |
| EP-2145540-A1 | Isothiazol carboxylic acid amides and their use in the protection of plants | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| EP-2145539-A1 | Isothiazolecarbamide derivatives for crop protection | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| EP-2132988-A1 | Isothiazole carboxylic acid amides and their use in the protection of plants | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |