SCHEMBL44256

SCHEMBL44256

Oc1nc2ccccc2c(I)c1I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 5/20 0.41
GLA P06280 5/20 0.41
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAOA P21397 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CHRM1 P11229 1/20 0.41
NQO2 P16083 1/20 0.41
DRD1 P21728 1/20 0.41
ACHE P22303 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10527280 0.82 MAOA (0.57) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL525342 0.82 MAOA (0.52) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL7552792 0.82 GPR3 (0.44) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL13445183 0.79 KDM4E (0.56) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL27110189 0.77 KDM4E (0.44) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL7607540 0.75 GPR3 (0.54) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL9980118 0.74 ALDH1A1 (0.52) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL28158574 0.74 KDM4E (0.41) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL851828 0.73 KDM4E (0.44) KDM4EALDH1A1GLAHPGDSMN1; SMN2
SCHEMBL311283 0.73 KDM4E (0.44) KDM4EALDH1A1GLAHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
WO-2025080590-A1 CO-CRYSTALLIZATION OF ACTIVES WITH SACCHARIDE-BASED MOLECULAR FRAMEWORKS SCIENTIFIC HORIZONS CONSULTING LLC (US) 2025-04-17 WO claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20240173512-A1 METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS STREETERVILLE CAPITAL, LLC 2024-05-30 US claimed
US-20240066022-A1 DIIODOHYDROXYQUINOLINE FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION PURDUE RESEARCH FOUNDATION (US) 2024-02-29 US claimed
US-11890421-B2 Methods for potentiating antimicrobial agents BEYOND AIR LTD (IL) 2024-02-06 US claimed
EP-4232004-A1 FRACTAL FORMULATIONS Nanogyre Sprl (BE) 2023-08-30 EP claimed
EP-3113843-B1 COMPOSITION AND METHOD FOR ENHANCING WOUND HEALING TUFFLEY MARK (AU) 2022-12-14 EP claimed
WO-2021078412-A1 FRACTAL FORMULATIONS MESSADEK JALLAL (BE) 2021-04-29 WO claimed
US-20210100787-A1 DIIODOHYDROXYQUINOLINE FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION PURDUE RESEARCH FOUNDATION (US) 2021-04-08 US claimed
CN-1960763-A Anti-vaginitis compositions EDKO TRADING REPRESENTATION (TR) 2007-05-09 CN claimed
CN-1826129-A Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS INC (US) 2006-08-30 CN claimed
CN-1703206-A Plaster for the treatment of dysfunctions and disorders of nail growth TROMMSDORFF ARZNEIMITTEL (DE) 2005-11-30 CN claimed
WO-2005087270-A1 ANTI-VAGINITIS COMPOSITIONS COMPRISING A TRIAZOLE EDKO TRADING AND REPRESENTATION CO. LTD. (TR) 2005-09-22 WO claimed
CN-1575165-A Plaster for the treatment of dysfunctions and disorders of nails, comprising sertaconazole TROMMSDORFF ARZNEIMITTEL (DE) 2005-02-02 CN claimed
CN-1324607-A Anti-fungus agent for local treatment of fungus infection of finger and its peripheral tissue and controllable releasable system of keratin-dissolving agnt TARO PHARMA IND (IL) 2001-12-05 CN claimed
WO-2001079349-A1 UREA MOULDING COMPOUNDS WITH ANTISEPTIC ACTIVITY PERSTORP CHEMITEC S.P.A. (IT) 2001-10-25 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-0305968-A2 Compositions against protozoal diseases YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1989-03-08 EP claimed
US-4485091-A HYDROGEN PEROXIDE, OIL IN WATER EMULSION QUINODERM LIMITED (GB) 1984-11-27 US claimed