Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13445500 | 0.93 | KMT2A (0.65) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL28126890 | 0.84 | KMT2A (0.53) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL13445493 | 0.83 | LMNA (0.49) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL28841141 | 0.82 | KMT2A (0.51) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL9249738 | 0.81 | KMT2A (0.52) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL438314 | 0.80 | MEN1 (0.70) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL28489704 | 0.80 | KMT2A (0.49) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL8328530 | 0.80 | LMNA (0.63) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL6464103 | 0.77 | MAPT (0.44) | KMT2AMAPTLMNAKDM4EHSP90AA1 | |
| SCHEMBL14811753 | 0.77 | MEN1 (0.64) | KMT2AMAPTLMNAKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683202-B2 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-7683202-B2 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080249252-A1 | New permanent surface modifiers | PICCINELLI PIERO | 2008-10-09 | — | — | US | disclosed |
| US-20080249252-A1 | New permanent surface modifiers | PICCINELLI PIERO | 2008-10-09 | — | — | US | disclosed |
| US-7408077-B2 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7408077-B2 | Permanent surface modifiers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249252-A1 | New permanent surface modifiers | SGMS1, SGMS2, PLIN5 | KMT2A 1186/4885MAPT 1142/4885LMNA 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.