Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097924 | 0.88 | LMNA (0.53) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL28126890 | 0.84 | KMT2A (0.53) | LMNAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL28841141 | 0.82 | KMT2A (0.51) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL438314 | 0.80 | MEN1 (0.70) | LMNAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL934472 | 0.80 | MAPT (0.59) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL28489704 | 0.80 | KMT2A (0.49) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL13445494 | 0.80 | KMT2A (0.56) | LMNAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8734497 | 0.79 | KMT2A (0.48) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL23204862 | 0.79 | KMT2A (0.45) | LMNATDP1KDM4EALDH1A1MAPT | |
| SCHEMBL21514715 | 0.79 | KMT2A (0.45) | LMNATDP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848947-B1 | Compositions containing a derivative of dibenzoylmethane, a derivative of 1,3,4-triazine and an dialkly benyalmalonate | OREAL (FR) | 1999-08-11 | — | — | EP | claimed |
| US-5882634-A | COSMETICS AND SKINS | SOCIETE L'OREAL S.A. (FR) | 1999-03-16 | — | — | US | claimed |
| US-5670140-A | SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE | L'OREAL (FR) | 1997-09-23 | — | — | US | claimed |
| US-5624663-A | Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates | L'OREAL (FR) | 1997-04-29 | — | — | US | claimed |
| US-5882634-A | COSMETICS AND SKINS | SOCIETE L'OREAL S.A. (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5670140-A | SKIN PROTECTION FOR COSMETICS FOR RADIATION RESISTANCE | L'OREAL (FR) | 1997-09-23 | — | — | US | disclosed |
| US-5624663-A | Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates | L'OREAL (FR) | 1997-04-29 | — | — | US | disclosed |