Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14739496 | 0.85 | ACHE (0.37) | TDP1MAPTMAPK1L3MBTL1ACHE | |
| SCHEMBL8010937 | 0.83 | ACHE (0.40) | TDP1ALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL276392 | 0.77 | HCAR2 (0.53) | MAPT | |
| SCHEMBL8336370 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AACHE | |
| SCHEMBL8336576 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AACHE | |
| SCHEMBL11174064 | 0.75 | MAPT (0.52) | MAPTMEN1KMT2AACHE | |
| SCHEMBL16976010 | 0.74 | ALDH1A1 (0.52) | TDP1ALDH1A1TSHRDDAH1MAPT | |
| SCHEMBL16411854 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TSHRDDAH1MAPTMEN1 | |
| SCHEMBL29182108 | 0.74 | MEN1 (0.57) | TDP1MAPTMEN1KMT2ACA12 | |
| SCHEMBL14685869 | 0.73 | GPR84 (0.43) | TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139553-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-09-22 | — | — | US | disclosed |
| US-9139553-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-09-22 | — | — | US | disclosed |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-05-09 | — | — | US | disclosed |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-05-09 | — | — | US | disclosed |
| US-8309515-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-11-13 | — | — | US | disclosed |
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | TDP1 1043/4885ALDH1A1 4765/4885TSHR 3832/4885 |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | TDP1 1043/4885ALDH1A1 4765/4885TSHR 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.