Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AMPD3 | Q01432 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519960 | 0.84 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL9470496 | 0.83 | ALDH1A1 (0.53) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL27815124 | 0.82 | ALDH1A1 (0.42) | TDP1ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL27793740 | 0.82 | ALDH1A1 (0.42) | TDP1ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL13445862 | 0.80 | TDP1 (0.34) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL28670479 | 0.80 | MAPK1 (0.56) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL28554083 | 0.79 | ALDH1A1 (0.54) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL8017907 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL28428867 | 0.78 | ALDH1A1 (0.53) | TDP1ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL29094168 | 0.78 | TDP1 (0.61) | TDP1ALDH1A1TSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139553-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-09-22 | — | — | US | disclosed |
| US-9139553-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-09-22 | — | — | US | disclosed |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2013-05-09 | — | — | US | disclosed |
| US-8309515-B2 | Poly(ethylene oxide)-block-poly(ester) block copolymers | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-11-13 | — | — | US | disclosed |
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069295-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | TDP1 1043/4885ALDH1A1 4765/4885TSHR 3832/4885 |
| US-20130116428-A1 | NOVEL POLY(ETHYLENE OXIDE)-BLOCK-POLY(ESTER) BLOCK COPOLYMERS | EBPL, ELOB, DCLRE1B | TDP1 1043/4885ALDH1A1 4765/4885TSHR 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.