Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813578 | 0.79 | REN (0.44) | SLC22A12ITKREN | |
| SCHEMBL13132302 | 0.79 | REN (0.40) | SLC22A12ITKRENCNR1 | |
| SCHEMBL13448648 | 0.76 | REN (0.45) | ITKREN | |
| SCHEMBL2810132 | 0.75 | REN (0.41) | SLC22A12ITKRENCNR1 | |
| SCHEMBL27795796 | 0.74 | SLC22A12 (0.38) | SLC22A12RENCNR1 | |
| SCHEMBL13131771 | 0.71 | REN (0.65) | REN | |
| SCHEMBL13131761 | 0.70 | REN (0.64) | REN | |
| SCHEMBL18509080 | 0.70 | HSD11B1 (0.39) | REN | |
| SCHEMBL2809388 | 0.69 | REN (0.46) | REN | |
| SCHEMBL16546348 | 0.69 | REN (0.35) | SLC22A12ITKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168952-A1 | MORPHOLINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |