Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117532 | 0.84 | LMNA (0.64) | KDM4ELMNARAB9AKMT2ANPC1 | |
| SCHEMBL13450334 | 0.83 | THRB (0.63) | LMNAKMT2ATHRBMAPTSMN1; SMN2 | |
| SCHEMBL13366272 | 0.83 | RAB9A (0.64) | KDM4ERAB9AKMT2ANPC1HPGD | |
| SCHEMBL22218315 | 0.82 | KDM4E (0.65) | KDM4ERAB9AKMT2ANPC1MAPT | |
| SCHEMBL23573293 | 0.82 | KMT2A (0.67) | KDM4ERAB9AKMT2ANPC1EPHX2 | |
| SCHEMBL14032242 | 0.81 | RBP4 (0.61) | KDM4ELMNAKMT2AHPGDGAA | |
| SCHEMBL28451751 | 0.81 | FAAH (0.53) | KDM4EKMT2ATHRBHPGDFAAH | |
| SCHEMBL30141405 | 0.81 | FAAH (0.53) | KDM4EKMT2ATHRBHPGDFAAH | |
| SCHEMBL20236493 | 0.79 | RAB9A (0.59) | KDM4ERAB9AKMT2ANPC1GAA | |
| SCHEMBL30576775 | 0.79 | POLB (0.60) | KDM4ERAB9AKMT2ANPC1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-B1 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-03-03 | — | — | EP | disclosed |