SCHEMBL1345175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23037281	0.84	TOP2A (0.47)	STAT3HTTADRB2AKR1C3AKR1C2
	SCHEMBL9564459	0.79	MEN1 (0.40)	HTTADRB2SMN1; SMN2USP2TP53
	SCHEMBL7122780	0.79	ALDH1A1 (0.43)	STAT3HTTADRB2TP53HSD17B10
	SCHEMBL9564488	0.79	MEN1 (0.38)	SMN1; SMN2ALDH1A1LMNAKMT2A
	SCHEMBL1342796	0.78	GSK3B (0.49)	ADRB2
	SCHEMBL1342791	0.77	NOS2 (0.40)	HTTADRB2RAB9ANPC1SMN1; SMN2
	SCHEMBL1342799	0.77	NOS2 (0.40)	HTTADRB2RAB9ANPC1ALDH1A1
	SCHEMBL7844447	0.77	STAT3 (0.48)	STAT3ADRB2RAB9ANPC1SMN1; SMN2
	SCHEMBL9561861	0.77	ADRB2 (0.43)	STAT3ADRB2RAB9ANPC1USP2
	SCHEMBL9564509	0.75	MEN1 (0.38)	HTTSMN1; SMN2USP2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.