Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 3/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23037281 | 0.89 | TOP2A (0.47) | ADRB2TOP2ATOP2BKMT2ASTAT3 | |
| SCHEMBL7122780 | 0.84 | ALDH1A1 (0.43) | ADRB2TOP2ATOP2BKMT2ASTAT3 | |
| SCHEMBL7844447 | 0.81 | STAT3 (0.48) | ADRB2TOP2ATOP2BKMT2AMEN1 | |
| SCHEMBL9564487 | 0.78 | MEN1 (0.43) | ADRB2TOP2ATOP2BKMT2AMEN1 | |
| SCHEMBL1345175 | 0.77 | STAT3 (0.44) | ADRB2TOP2ATOP2BKMT2ASTAT3 | |
| SCHEMBL9849851 | 0.76 | TOP2A (0.50) | ADRB2TOP2ATOP2B | |
| SCHEMBL9564450 | 0.75 | MEN1 (0.40) | TOP2ATOP2BKMT2AMEN1USP2 | |
| SCHEMBL8096676 | 0.72 | TOP2A (0.47) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL9564502 | 0.70 | MEN1 (0.39) | KMT2AMEN1USP2ALDH1A1GRK6 | |
| SCHEMBL30995245 | 0.70 | LMNA (0.37) | RAB9AUSP2NPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5155847-A | — | — | None | — | — | JP | disclosed |
| US-5182401-A | Bactericide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | disclosed |