Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.41 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.41 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417279 | 0.89 | MMP8 (0.47) | MMP8CYP4Z1CYP4F11CYP4F12ALDH1A1 | |
| SCHEMBL1417367 | 0.89 | CYP4Z1 (0.50) | MMP8CYP4Z1CYP4F11CYP4F12CYP4F2 | |
| SCHEMBL1682154 | 0.79 | MMP8 (0.50) | MMP8ALDH1A1TSHRTP53NPY1R | |
| SCHEMBL3779327 | 0.77 | MMP8 (0.45) | MMP8ALDH1A1TSHRTP53NPY1R | |
| SCHEMBL9543295 | 0.76 | PTGS1 (0.49) | ALDH1A1TSHRALOX5HSD17B10 | |
| SCHEMBL1312803 | 0.75 | MMP8 (0.62) | MMP8CYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL4779871 | 0.75 | MMP8 (0.59) | MMP8ALDH1A1MAPK1TDP1TP53 | |
| SCHEMBL15262696 | 0.74 | ALDH1A1 (0.43) | MMP8ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL15261621 | 0.74 | SMN1; SMN2 (0.51) | MMP8CYP4F2CYP4A11ALDH1A1TSHR | |
| SCHEMBL4128844 | 0.74 | CA12 (0.54) | CYP4Z1CYP4F11CYP4F12CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264925-A1 | METHOD FOR PRODUCING PYRAZOLE GLYCOSIDE DERIVATIVES | SANOFI (FR) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264925-A1 | METHOD FOR PRODUCING PYRAZOLE GLYCOSIDE DERIVATIVES | CYP2F1, CYP4F3, F11 | MMP8 2345/4885CYP4Z1 177/4885CYP4F11 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.