SCHEMBL13455451

SCHEMBL13455451

C=C(C)c1ccccc1OP(Oc1c(C)cc(C)cc1-c1cc(C)cc(C)c1OP(Oc1ccccc1C(=C)C)c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14269175 0.91 ATM (0.34)
SCHEMBL13799586 0.78 L3MBTL1 (0.31) MEN1KMT2A
SCHEMBL10309813 0.78 TDP1 (0.33)
SCHEMBL3418221 0.75 CYP1A2 (0.38) MEN1KMT2A
SCHEMBL2603380 0.73 LMNA (0.39) MEN1KMT2A
SCHEMBL13385705 0.73 HSD11B1 (0.30)
SCHEMBL13199356 0.73 NPSR1 (0.35) MEN1KMT2A
SCHEMBL12809508 0.72 IDO1 (0.32)
SCHEMBL13199358 0.72 APEX1 (0.32)
SCHEMBL13199354 0.70 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671229-B2 Obtained from liquefied petroleum gas; nonoxidative catalytic dehydrogenation of n-butane to give 1-butene, 2-butene, and 1,3-butadiene; oxidative dehydrogenation of 1-butene and 2-butene to unstabilized 1,3-butadiene; distilling; hydrocyanation preferably over a nickel (0) tris(phosphite) complex BASF SE (DE) 2010-03-02 US disclosed