Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799586 | 0.90 | L3MBTL1 (0.31) | LMNAL3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL10309813 | 0.74 | TDP1 (0.33) | L3MBTL1ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL3418221 | 0.74 | CYP1A2 (0.38) | LMNAL3MBTL1TDP1TSHRNPSR1 | |
| SCHEMBL13455451 | 0.73 | ABCB1 (0.32) | KMT2AMEN1 | |
| SCHEMBL4433002 | 0.73 | L3MBTL1 (0.39) | LMNAL3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13199356 | 0.72 | NPSR1 (0.35) | LMNAL3MBTL1TSHRNPSR1KMT2A | |
| SCHEMBL13199358 | 0.71 | APEX1 (0.32) | KDM4E | |
| SCHEMBL14521866 | 0.71 | IDO1 (0.31) | — | |
| SCHEMBL13385705 | 0.70 | HSD11B1 (0.30) | — | |
| SCHEMBL3961009 | 0.70 | LMNA (0.48) | LMNAL3MBTL1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633700-B1 | DINITRILE PREPARATION METHOD | INVISTA TECH SARL (CH) | 2012-04-25 | — | — | EP | disclosed |
| US-7897801-B2 | Process for the preparation of dinitriles | INVISTA NORTH AMERICA S.A R.L. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897801-B2 | Process for the preparation of dinitriles | INVISTA NORTH AMERICA S.A R.L. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7777068-B2 | Ni(0) -containing catalyst system | BASF SE (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7612223-B2 | Process for the hydrocyanation of unsaturated compounds | INVISTA NORTH AMERICA S.A R.L. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612223-B2 | Process for the hydrocyanation of unsaturated compounds | INVISTA NORTH AMERICA S.A R.L. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1622863-B1 | METHOD FOR THE HYDROCYANATION OF UNSATURATED COMPOUNDS | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2008-08-13 | — | — | EP | disclosed |
| US-20080071105-A1 | NI(0) -CONTAINING CATALYST SYSTEM | BASF SE (DE) | 2008-03-20 | — | — | US | disclosed |
| US-7345006-B2 | Catalyst system containing Ni(0) for hydrocyanation | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345006-B2 | Catalyst system containing Ni(0) for hydrocyanation | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | INV NYLON CHEMICALS AMERICAS, LLC | 2007-11-08 | — | — | US | disclosed |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | INV NYLON CHEMICALS AMERICAS, LLC | 2007-11-08 | — | — | US | disclosed |
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | INV NYLON CHEMICALS AMERICAS, LLC | 2007-07-05 | — | — | US | disclosed |
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | INV NYLON CHEMICALS AMERICAS, LLC | 2007-07-05 | — | — | US | disclosed |
| EP-1438132-B1 | Phosphonites used in catalyst systems for the addition of prussic acid to olefinic double bonds and for the isomerisation of organic nitriles | BASF AG (DE) | 2007-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155979-A1 | Process for the hydrocyanation of unsaturated compounds | DDT, DBN1, HPD | LMNA 847/4885L3MBTL1 1921/4885ALDH1A1 1091/4885 |
| US-20070260086-A1 | Process for the Preparation of Dinitriles | DDT, NIT2, NOS2 | LMNA 1728/4885L3MBTL1 4457/4885ALDH1A1 1911/4885 |
| US-20080071105-A1 | NI(0) -CONTAINING CATALYST SYSTEM | C1R, XDH, CBR1 | LMNA 715/4885L3MBTL1 2732/4885ALDH1A1 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.