SCHEMBL1346040

SCHEMBL1346040

FC(F)(F)c1cc(-c2nccn2-c2ccccc2)[nH]n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
ALOX15B O15296 1/20 0.40
KDR P35968 5/20 0.37
FLT1 P17948 2/20 0.36
FLT4 P35916 2/20 0.36
PTGS1 P23219 1/20 0.35
MAPK9 P45984 1/20 0.35
MAPK10 P53779 1/20 0.35
CYP1A2 P05177 4/20 0.35
RAF1 P04049 1/20 0.35
BRAF P15056 1/20 0.35
CYP3A4 P08684 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HTT P42858 1/20 0.33
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345719 0.80 CYP3A4 (0.40) L3MBTL1ALOX15BKDRMAPK9MAPK10
SCHEMBL1345570 0.77 HSD17B10 (0.47) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL1343637 0.75 CCNC (0.34) L3MBTL1NPC1RAB9A
SCHEMBL1345960 0.73 SCN4A (0.47) L3MBTL1MAPK9MAPK10CYP1A2CYP3A4
SCHEMBL19083037 0.72 OGA (0.30)
SCHEMBL14624000 0.72 RAB9A (0.55) L3MBTL1PTGS1NPC1RAB9ASMN1; SMN2
SCHEMBL17207300 0.71 KDR (0.56) L3MBTL1ALOX15BKDRFLT1FLT4
SCHEMBL29040464 0.70 MAPK9 (0.53) L3MBTL1ALOX15BKDRFLT1FLT4
SCHEMBL30460674 0.70 KDM4E (0.44) L3MBTL1CYP1A2CYP2D6CYP2C9NPC1
SCHEMBL27360696 0.70 CYP3A4 (0.39) L3MBTL1ALOX15BKDRMAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474071-A Platinum complex, organic light emitting diode and device capable of emitting visible light or near infrared light 季昀 2017-12-15 CN disclosed
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION NATIONAL TSING HUA UNIVERSITY (TW) 2017-12-07 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION OCIAD2, OCIAD1, OPRD1 L3MBTL1 879/4885ALOX15B 1280/4885KDR 2273/4885
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME OCIAD2, POF1B, OCIAD1 L3MBTL1 262/4885ALOX15B 872/4885KDR 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.