SCHEMBL1343637

SCHEMBL1343637

Cn1ccnc1-c1cc(C(F)(F)F)n[nH]1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CCNC P24863 1/20 0.34
CDK8 P49336 1/20 0.34
LPO P22079 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
BRD4 O60885 1/20 0.32
KDM4E B2RXH2 2/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.31
PKM P14618 1/20 0.31
MCL1 Q07820 1/20 0.30
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19083037 0.81 OGA (0.30)
SCHEMBL1345649 0.78 LPO (0.38) CCNCCDK8LPONPC1RAB9A
SCHEMBL2685399 0.76 CCR1 (0.48) KDM4ELRRK2
SCHEMBL1346040 0.75 L3MBTL1 (0.40) NPC1RAB9AL3MBTL1
SCHEMBL15375205 0.74 CA2 (0.33)
SCHEMBL1345570 0.72 HSD17B10 (0.47) BRD4HSD17B10
SCHEMBL16743581 0.72 HSP90AA1 (0.37) KDM4EHSD17B10
SCHEMBL15508049 0.71 CA2 (0.33)
SCHEMBL3728805 0.71 LRRK2 (0.41) NPC1RAB9ABRD4MCL1LRRK2
SCHEMBL16691670 0.70 IDO1 (0.36) KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474071-A Platinum complex, organic light emitting diode and device capable of emitting visible light or near infrared light 季昀 2017-12-15 CN disclosed
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION NATIONAL TSING HUA UNIVERSITY (TW) 2017-12-07 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-8586201-B2 Light-emitting element and iridium complex CHIMEI INNOLUX CORPORATION (TW) 2013-11-19 US disclosed
US-8586201-B2 Light-emitting element and iridium complex CHIMEI INNOLUX CORPORATION (TW) 2013-11-19 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-8062767-B2 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2011-11-22 US disclosed
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2010-06-10 US disclosed
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2010-06-10 US disclosed
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2010-06-10 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
US-20080217606-A1 Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter Cheng, Chien-Hong (TW) 2008-09-11 US disclosed
CN-101215468-A Light-emitting component iridium complex compound CHI MEI OPTOELECTRONICS CO LTD (CN) 2008-07-09 CN disclosed
US-20070141394-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2007-06-21 US disclosed
US-20070141394-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2007-06-21 US disclosed
US-20070141394-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX CHI MEI OPTOELECTRONICS CORP. (TW) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170352822-A1 PLATINUM BASED OLED EMITTER SHOWING VISIBLE OR NEAR-INFRARED EMISSION OCIAD2, OCIAD1, OPRD1 CCNC 489/4885CDK8 2274/4885LPO 2870/4885
US-20100141133-A1 LIGHT-EMITTING ELEMENT AND IRIDIUM COMPLEX AP3D1, INF2, CRY1 CCNC 1431/4885CDK8 3036/4885LPO 2047/4885
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME OCIAD2, POF1B, OCIAD1 CCNC 1209/4885CDK8 4156/4885LPO 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.