Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125526 | 0.76 | KIF11 (0.45) | KIF11LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL28311749 | 0.76 | CYP2C9 (0.41) | LMNASMN1; SMN2NPSR1CYP3A4MEN1 | |
| SCHEMBL13460576 | 0.74 | MAPT (0.35) | LMNAHTTSMN1; SMN2NPSR1NPC1 | |
| SCHEMBL13460534 | 0.72 | TP53 (0.39) | LMNAGAASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL16937827 | 0.72 | ACHE (0.40) | KIF11LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL22932513 | 0.71 | ACHE (0.50) | KIF11LMNANPC1RAB9AHTR3E | |
| SCHEMBL16401448 | 0.70 | TAAR1 (0.50) | SMN1; SMN2NPC1RAB9ACTBP2TAAR1 | |
| SCHEMBL30394051 | 0.70 | TAAR1 (0.50) | SMN1; SMN2NPC1RAB9ACTBP2TAAR1 | |
| SCHEMBL6273920 | 0.70 | CES2 (0.44) | KIF11LMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL8367527 | 0.70 | ACHE (0.48) | KIF11LMNAHTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023946-A1 | NOVEL URACIL COMPOUND HAVING NITROGENATED HETEROCYCLIC RING OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2010-03-04 | — | — | WO | disclosed |