Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18943205 | 0.80 | TRPA1 (0.44) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL4641824 | 0.80 | TRPA1 (0.44) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL11526523 | 0.75 | LMNA (0.41) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL29016298 | 0.75 | LMNA (0.41) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL7765727 | 0.75 | LMNA (0.42) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL10894861 | 0.73 | HPGD (0.40) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL3433198 | 0.73 | AKR1C3 (0.48) | TRPA1LMNAHPGDMAPK1CYP2D6 | |
| SCHEMBL10894864 | 0.73 | HPGD (0.40) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL22319193 | 0.72 | TRPA1 (0.39) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL9271112 | 0.71 | KDM4E (0.48) | TRPA1LMNAADRA2CKDM4EADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664056-B1 | FUSED PENTACYCLIC POLYETHERS | UNIV NORTH CAROLINA AT WILMING (US) | 2010-03-03 | — | — | EP | disclosed |