Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18943205 | 0.80 | TRPA1 (0.44) | LMNAMAPK1TSHRTRPA1KDM4E | |
| SCHEMBL4641824 | 0.80 | TRPA1 (0.44) | LMNAMAPK1TSHRTRPA1KDM4E | |
| SCHEMBL20356276 | 0.78 | LMNA (0.43) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL9656453 | 0.78 | LMNA (0.46) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL9656438 | 0.78 | LMNA (0.46) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL11879383 | 0.76 | LMNA (0.44) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL28444792 | 0.75 | LMNA (0.44) | LMNATRPA1CES2CES1 | |
| SCHEMBL29016298 | 0.75 | LMNA (0.41) | LMNATSHRTRPA1KDM4EL3MBTL1 | |
| SCHEMBL11526523 | 0.75 | LMNA (0.41) | LMNATSHRTRPA1KDM4EL3MBTL1 | |
| SCHEMBL13460568 | 0.75 | TRPA1 (0.44) | LMNAMAPK1TSHRTRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816477-B1 | INTERNAL-COMBUSTION ENGINE OIL COMPOSITION | IDEMITSU KOSAN CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-5965495-A | BASE OIL; ASHLESS DISPERSANT CONTAINING BORON IN A SPECIFIC AMOUNT OR MORE RELATIVE TO THE TOTAL METAL CONTENT; METALLIC DETERGENT; OXIDATION STABILITY, LOW SULFATED ASH; RESISTANCE TO COKING; APPARATUS FOR EXHAUST GAS TREATMENT NOT AFFECTED | IDEMITSU KOSAN CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0816477-A1 | INTERNAL-COMBUSTION ENGINE OIL COMPOSITION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5672570-A | DECREASED ASH CONTENT; DETERGENCY | IDEMITSU KOSAN CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| US-5525247-A | CONTAINING BORON-CONTAINING DISPERSANT AND DETERGENT | IDEMITSU KOSAN CO., LTD. (JP) | 1996-06-11 | — | — | US | disclosed |