Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19825999 | 0.87 | SMN1; SMN2 (0.46) | CA12CA1CA2CA9HTT | |
| SCHEMBL8164496 | 0.79 | RXFP1 (0.62) | IDO1CA12CA1CA2CA9 | |
| SCHEMBL12209638 | 0.78 | MAPT (0.60) | CA12CA1CA2CA9HTT | |
| SCHEMBL10057892 | 0.78 | TDP1 (0.60) | SIGMAR1HTTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL12973183 | 0.76 | MAPT (0.54) | CA12CA1CA2CA9HTT | |
| SCHEMBL13424786 | 0.76 | MEN1 (0.52) | IDO1HTTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL669782 | 0.76 | SMN1; SMN2 (0.67) | CA12CA1CA2CA9HTT | |
| SCHEMBL22384713 | 0.76 | NPC1 (0.43) | CA12CA1CA2CA9HTT | |
| SCHEMBL20725724 | 0.76 | ALDH1A1 (0.52) | HTTSMN1; SMN2EPHX1MEN1ALDH1A1 | |
| SCHEMBL28294619 | 0.76 | TAS2R38 (0.60) | IDO1SIGMAR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024356-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE HAVING NAPHTHYRIDINE-N-OXIDE | 大正製薬株式会社 (JP) | 2010-03-04 | — | — | WO | disclosed |